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[苯及其同系物给药后大脑多个结构的冲动神经元活动]

[Impulsive neuron activity of several structures of the brain after administration of benzene and its homologues].

作者信息

Korytov L I

出版信息

Biull Eksp Biol Med. 1990 Jul;110(7):17-9.

PMID:2224086
Abstract

The obtained findings have shown that dominating inter-impulse intervals in the area of 1000 and more ms, and multimodality of their distribution occur in benzene, toluol, xylol injection within time-structure of some neurons activity of sensomotor cortex, hippocampus, thalamus and lateral hypothalamus. The particularities of neuronal activity of the studied structures were revealed by the injection of chemical substances in natural and artificially produced food motivation. The mechanism of neurons activity blockade in benzene and its homologous injection was suggested to be linked with their influence upon mediator process, and perhaps, peptide factors participating in the formation of neuronal activity.

摘要

所获得的研究结果表明,在感觉运动皮层、海马体、丘脑和下丘脑外侧某些神经元活动的时间结构内,苯、甲苯、二甲苯注射后会出现1000毫秒及以上的主要脉冲间期,且其分布具有多模态性。通过在自然和人工产生的食物动机中注射化学物质,揭示了所研究结构的神经元活动特性。苯及其同系物注射导致神经元活动阻断的机制被认为与其对介质过程的影响有关,或许还与参与神经元活动形成的肽类因子有关。

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