• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Patients with arthritis and anti-U1-RNP antibodies: a 10-year follow-up.

作者信息

Piirainen H I

机构信息

Kivelä Municipal Hospital, Helsinki, Finland.

出版信息

Br J Rheumatol. 1990 Oct;29(5):345-8. doi: 10.1093/rheumatology/29.5.345.

DOI:10.1093/rheumatology/29.5.345
PMID:2224402
Abstract

Five hundred and forty patients attending a rheumatology ward were screened for antinuclear antibodies (ANA) by indirect immunofluorescence (IFL). Seventy had a significant titre of ANA. Twenty-three had U1-ribonucleoprotein antibodies (U1-RNP-ab). The clinical findings in U1-RNP-ab-positive patients were consistent with mixed connective tissue disease (MCTD). Disease was more serious in the U1-RNP-ab-positive patients in terms of polyarthritis severity as well as mortality due to rheumatic disease. Thus, in this arthritis patient population, U1-RNP-ab positivity predicted an aggressive disease characterized by an erosive arthritis.

摘要

相似文献

1
Patients with arthritis and anti-U1-RNP antibodies: a 10-year follow-up.
Br J Rheumatol. 1990 Oct;29(5):345-8. doi: 10.1093/rheumatology/29.5.345.
2
Serial estimation of anti-RNP antibody titers in systemic lupus erythematosus, mixed connective tissue disease and rheumatoid arthritis.系统性红斑狼疮、混合性结缔组织病和类风湿关节炎中抗RNP抗体滴度的系列评估
J Clin Lab Immunol. 1984 Jan;13(1):15-9.
3
Anti-ribonucleoprotein antibodies in inflammatory rheumatic diseases.炎症性风湿性疾病中的抗核糖核蛋白抗体。
Scand J Rheumatol. 1984;13(2):177-80. doi: 10.3109/03009748409100383.
4
T-cell epitopes on the 70-kDa protein of the (U1)RNP complex in autoimmune rheumatologic disorders.自身免疫性风湿性疾病中（U1）RNP复合物70-kDa蛋白上的T细胞表位
J Autoimmun. 1990 Dec;3(6):747-57. doi: 10.1016/s0896-8411(05)80041-1.
5
[Sharp's syndrome. Clinical, immunological and nosographic aspects].[夏普综合征。临床、免疫学及疾病分类学方面]
Minerva Med. 1980 Dec 15;71(50):3655-63.
6
Clinical significance of U1-RNP immune complexes in mixed connective tissue disease and systemic lupus erythematosus.U1 - RNP免疫复合物在混合性结缔组织病和系统性红斑狼疮中的临床意义
Rheumatol Int. 1987;7(1):7-11. doi: 10.1007/BF00267336.
7
Comparative study of 4 diagnosis criteria sets for mixed connective tissue disease in patients with anti-RNP antibodies. Autoimmunity Group of the Hospitals of Toulouse.抗RNP抗体患者混合性结缔组织病4种诊断标准集的比较研究。图卢兹医院自身免疫研究组。
J Rheumatol. 1996 Dec;23(12):2055-62.
8
Clinical characteristics and course in patients with high titer anti-RNP antibodies.高滴度抗RNP抗体患者的临床特征及病程
J Rheumatol. 1982 Jul-Aug;9(4):536-42.
9
Blotting patterns of IgG anti-(U1)RNP antibodies in mixed connective tissue disease.混合性结缔组织病中IgG抗（U1）RNP抗体的印迹模式。
Rheumatol Int. 1996;16(4):145-50. doi: 10.1007/BF01419727.
10
Antibodies to heterogeneous nuclear ribonucleoproteins in sera from patients with rheumatic autoimmune diseases.风湿性自身免疫病患者血清中针对不均一核核糖核蛋白的抗体。
J Clin Immunol. 1984 May;4(3):209-19. doi: 10.1007/BF00914968.

引用本文的文献

1
Mixed connective tissue disease: Not always an obvious diagnosis.混合性结缔组织病：诊断并非总是一目了然。
Clin Case Rep. 2020 Jun 17;8(10):1979-1983. doi: 10.1002/ccr3.3045. eCollection 2020 Oct.
2
[A patient with mixed collagen disease, antiphospholipid syndrome and Sjögren syndrome].一名患有混合性胶原病、抗磷脂综合征和干燥综合征的患者。
Med Klin (Munich). 1998 Jan 15;93(1):34-8. doi: 10.1007/BF03045038.
3
Widespread vasculopathy with hemolytic uremic syndrome, perimyocarditis and cystic pancreatitis in a young woman with mixed connective tissue disease. Case report and review of the literature.
一名患有混合性结缔组织病的年轻女性出现伴有溶血性尿毒症综合征、心肌外层炎和胰腺囊肿性炎症的广泛性血管病变。病例报告及文献综述
Rheumatol Int. 1993;13(1):31-6. doi: 10.1007/BF00290331.