使用空气连续流动无金属氧化吡啶。
Continuous flow metal-free oxidation of picolines using air.
机构信息
Chemical Process Research Laboratories, Fukui Research Institute, Ono Pharmaceutical Co., Ltd., 50-10 Yamagishi, Mikuni, Sakai, Fukui 913-0032, Japan.
出版信息
Chem Commun (Camb). 2012 Feb 18;48(15):2086-8. doi: 10.1039/c2cc17123f. Epub 2012 Jan 13.
PMID:22246388
Abstract
The metal free, direct oxidation of 2-, 3-, and 4-picoline to the corresponding carboxylic acid using either oxygen or air has been developed under continuous flow conditions. Complete conversion for all three substrates was obtained at moderate temperatures and pressures within minutes.
摘要
在连续流条件下，开发了一种无金属、直接将 2-、3-和 4-吡啶氧化为相应羧酸的方法，可使用氧气或空气。在温和的温度和压力下，所有三种底物都能在数分钟内完全转化。
Zotero 插件