Gradishar W J, Vokes E E, Ni K, Panje W R
Department of Medicine, University of Chicago, Illinois.
Cancer. 1990 Nov 1;66(9):1914-8. doi: 10.1002/1097-0142(19901101)66:9<1914::aid-cncr2820660910>3.0.co;2-g.
A 62-year-old woman who was being treated for squamous cell carcinoma of the head and neck developed a chemotherapy-related hemolytic-uremic syndrome during the second cycle of neoadjuvant chemotherapy consisting of cisplatin, bleomycin, and methotrexate. Though the syndrome was suspected early, attempts at reversing the hematologic and renal abnormalities were unsuccessful. At postmortem examination, the characteristic microvascular lesions of the hemolytic-uremic syndrome were found in the kidneys.
一名62岁的女性正在接受头颈部鳞状细胞癌的治疗，在由顺铂、博来霉素和甲氨蝶呤组成的新辅助化疗的第二个周期中出现了化疗相关的溶血尿毒综合征。尽管该综合征早期就被怀疑，但逆转血液学和肾脏异常的尝试未成功。尸检时，在肾脏中发现了溶血尿毒综合征的特征性微血管病变。
