Kubík A, Reissigová J
Výzkumný ústav tuberkulózy a respiracních nemocí, Praha.
Cas Lek Cesk. 1990 Sep 28;129(39):1217-23.
The mortality from malignant tumours of the respiratory system in men in the Czech Republik increased steeply during 1950-1967 from the initial value of 22.3 per 100,000 men to more than triple, while in women the values persisted during this period with minor accidental deviations at a level of cca 5.7 per 100,000 women (with standardization for the world population). During the subsequent 20-year period there was a rising trend in both sexes; in 1987 the value for men was 77.4 per 100,000, for women 9.1 per 100,000. The age-specific mortality from malignant tumours of the respiratory system had in none of the evaluated age groups of men and women a declining trend, while in the USA and in Great Britain in younger men and in the group of youngest women a decline is recorded. The cigarette consumption in the Czech Republic after the Second World War increased steeply to the end of the sixties; in 1971-1987 it did not rise further and varied mostly within the range of 19 and 20 billion cigarettes per year, i. e. 2500 cigarettes per inhabitant above 15 years of age, regardless whether he smoked or not. To change the hitherto adverse development of mortality from malignant tumours of the respiratory system it is essential to reduce in the first place the intoxication of the population with carcinogens of tobacco smoke, by influencing smoking habits and by reducing carcinogenic substances in cigarettes and by some modifications of the working and living environment, by provision of an optimal content of probably protective substances in foods and some other measures.
1950年至1967年期间,捷克共和国男性呼吸系统恶性肿瘤死亡率急剧上升,从最初的每10万名男性22.3例增至三倍多,而女性这一数值在此期间基本保持不变,每10万名女性约为5.7例(以世界人口进行标准化)。在随后的20年里,两性死亡率均呈上升趋势;1987年,男性死亡率为每10万名77.4例,女性为每10万名9.1例。在评估的男性和女性各年龄组中,呼吸系统恶性肿瘤的年龄别死亡率均无下降趋势,而在美国和英国,年轻男性及最年轻女性组的死亡率则呈下降趋势。第二次世界大战后,捷克共和国的香烟消费量急剧增加,直至60年代末;1971年至1987年期间,香烟消费量没有进一步上升,每年大多在190亿至200亿支之间波动,即15岁以上居民人均2500支,无论其是否吸烟。要改变呼吸系统恶性肿瘤死亡率目前的不利发展态势,首先必须通过影响吸烟习惯、减少香烟中的致癌物质、对工作和生活环境进行一些改善、在食物中提供可能具有保护作用的物质的最佳含量以及采取其他一些措施,来降低人群因烟草烟雾致癌物而产生的中毒情况。