Murdoch Childrens Research Institute, Royal Children's Hospital, Parkville, Melbourne, Australia.
Nutrients. 2010 Mar;2(3):389-407. doi: 10.3390/nu2030389. Epub 2010 Mar 23.
Low maternal vitamin D levels during pregnancy have been linked to various health outcomes in the offspring, ranging from periconceptional effects to diseases of adult onset. Maternal and infant cord 25(OH)D levels are highly correlated. Here, we review the available evidence for these adverse health effects. Most of the evidence has arisen from observational epidemiological studies, but randomized controlled trials are now underway. The evidence to date supports that women should be monitored and treated for vitamin D deficiency during pregnancy but optimal and upper limit serum 25(OH)D levels during pregnancy are not known.
孕期母体维生素 D 水平较低与后代的各种健康结果有关，从受孕前的影响到成年发病的疾病都有涉及。母体和婴儿脐带 25(OH)D 水平高度相关。在这里，我们回顾了这些不良健康影响的现有证据。大多数证据来自观察性的流行病学研究，但随机对照试验现在正在进行中。迄今为止的证据支持孕妇应在怀孕期间接受维生素 D 缺乏症的监测和治疗，但不知道怀孕期间最佳和上限血清 25(OH)D 水平。
