Department of Sports and Nutrition, Rīga Stradiņš University, 26a Anniņmuižas bulvāris, LV-1067 Riga, Latvia.
Riga East Clinical University Hospital, 2 Hipokrata Street, LV-1038 Riga, Latvia.
Nutrients. 2023 Aug 7;15(15):3493. doi: 10.3390/nu15153493.
Maternal vitamin D deficiency, which is highly prevalent in pregnant women in Europe, is linked to adverse health effects for both the mother and child. The objective was to assess vitamin D status in pregnant women by evaluating their dietary and supplemental vitamin D intake, serum vitamin D levels, parathyroid hormone levels, and lifestyle factors. This cross-sectional study, with a total of 735 participants (145 pregnant and 590 up to the seventh day postpartum), took place in Latvia. Blood samples, a food frequency questionnaire, and medical documentation were used for data collection. The median serum vitamin D concentration was 34.0 ng/mL, with pregnant women having higher levels (42.9 ng/mL) than postpartum women (31.8 ng/mL). There was no association between vitamin D serum concentration and dietary intake of vitamin D ( > 0.05), whereas there was a significant correlation with use of vitamin D supplements (r = 0.41; < 0.001 in pregnant women and r = 0.35; < 0.001 in postpartum women). This study demonstrated that a minority of pregnant women (21.9%) had optimal serum vitamin D concentration (>45 ng/mL), and diet had no significant impact on vitamin D levels. Thus, our proposed recommendation for vitamin D intake during pregnancy was 63 mcg (2500 IU) year-round for optimal levels in pregnant women in Northeastern Europe.
孕妇维生素 D 缺乏在欧洲的孕妇中非常普遍,与母婴的健康不良影响有关。目的是通过评估孕妇的饮食和补充维生素 D 摄入量、血清维生素 D 水平、甲状旁腺激素水平和生活方式因素来评估孕妇的维生素 D 状况。这是一项在拉脱维亚进行的横断面研究,共有 735 名参与者(145 名孕妇和 590 名产后 7 天内的妇女)。采集血样、食物频率问卷和医疗记录用于数据收集。血清维生素 D 浓度中位数为 34.0ng/mL,孕妇的水平(42.9ng/mL)高于产后妇女(31.8ng/mL)。维生素 D 血清浓度与维生素 D 的饮食摄入量之间没有关联(>0.05),而与维生素 D 补充剂的使用呈显著相关性(孕妇 r = 0.41;<0.001,产后妇女 r = 0.35;<0.001)。本研究表明,少数孕妇(21.9%)具有最佳的血清维生素 D 浓度(>45ng/mL),而饮食对维生素 D 水平没有显著影响。因此,我们建议在北欧地区孕妇全年摄入 63mcg(2500IU)的维生素 D,以达到最佳水平。