Longo W E, Touloukian R J, West A B, Ballantyne G H
Department of Surgery, Yale New Haven Hospital, Yale University School of Medicine, Connecticut.
Dis Colon Rectum. 1990 Nov;33(11):980-4. doi: 10.1007/BF02139111.
Juvenile polyps of the colon and rectum traditionally have been viewed as being benign inflammatory or harmartomatous lesions without potential for malignant change. The authors report a case of adenocarcinoma developing in a patient with sporadic juvenile polyposis. Juvenile polyposis was diagnosed in the patient at age 4 years. He underwent subtotal colectomy at age 6 years. At age 12, he underwent a proctectomy and a Swenson pull-through because of adenomatous changes in the rectal stump. At age 19 surveillance endoscopy revealed invasive cancer in a juvenile polyp.
传统上，结肠和直肠的幼年性息肉被视为良性炎症性或错构瘤性病变，无恶变可能。作者报告了1例散发性幼年性息肉病患者发生腺癌的病例。该患者4岁时被诊断为幼年性息肉病。6岁时接受了结肠次全切除术。12岁时，因直肠残端出现腺瘤样改变，接受了直肠切除术和斯文森拖出术。19岁时，监测性内镜检查发现1枚幼年性息肉中有浸润性癌。
