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遗传性全身性幼年性息肉病:与动静脉畸形及恶性肿瘤风险的关联

Hereditary generalized juvenile polyposis: association with arteriovenous malformations and risk of malignancy.

作者信息

Radin D R

机构信息

Department of Radiology, LA County-USC Medical Center 90033-1084.

出版信息

Abdom Imaging. 1994 Mar-Apr;19(2):140-2. doi: 10.1007/BF00203488.

DOI:10.1007/BF00203488
PMID:8199545
Abstract

A young man with hereditary juvenile polyposis, a duodenal adenoma with carcinoma in situ, and multiple arteriovenous malformations of the lungs and liver is reported. Because of the risk of malignancy, it is suggested that patients with juvenile polyposis have endoscopic or radiographic surveillance of the upper gastrointestinal tract in addition to either prophylactic colectomy or regular colonoscopic surveillance with polypectomy. In view of the serious potential complications of associated pulmonary, cerebral, and hepatic arteriovenous malformations, screening of patients with juvenile polyposis with chest radiography, magnetic resonance imaging of the brain, and sonography of the liver may be warranted.

摘要

报道了一名患有遗传性青少年息肉病、原位癌十二指肠腺瘤以及肺部和肝脏多发动静脉畸形的年轻男性。鉴于存在恶性肿瘤风险,建议青少年息肉病患者除了进行预防性结肠切除术或定期结肠镜检查及息肉切除外,还应对上消化道进行内镜或影像学监测。鉴于相关肺部、脑部和肝脏动静脉畸形存在严重的潜在并发症,对青少年息肉病患者进行胸部X线摄影、脑部磁共振成像以及肝脏超声检查筛查可能是必要的。

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Hereditary generalized juvenile polyposis: association with arteriovenous malformations and risk of malignancy.遗传性全身性幼年性息肉病:与动静脉畸形及恶性肿瘤风险的关联
Abdom Imaging. 1994 Mar-Apr;19(2):140-2. doi: 10.1007/BF00203488.
2
Hereditary generalized juvenile polyposis associated with pulmonary arteriovenous malformation.与肺动静脉畸形相关的遗传性全身性幼年性息肉病。
Gastroenterology. 1980 Jun;78(6):1566-70.
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Unusual complications after embolization of a pulmonary arteriovenous malformation.肺动静脉畸形栓塞术后的罕见并发症。
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Nihon Kokyuki Gakkai Zasshi. 2009 Dec;47(12):1103-7.
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Generalized juvenile polyposis with pulmonary arteriovenous malformations and hypertrophic osteoarthropathy.伴有肺动静脉畸形和肥厚性骨关节病的广义青少年息肉病。
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Hereditary hemorrhagic telangiectasia associated with pulmonary arteriovenous malformations presenting as hemothorax.遗传性出血性毛细血管扩张症合并肺动静脉畸形并表现为血胸。
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Does any lower gastrointestinal bleeding in patients suffering from hereditary hemorrhagic telangiectasia (Osler-Weber-Rendu) necessitate a full colonic visualization?患有遗传性出血性毛细血管扩张症(奥斯勒-韦伯-伦杜综合征)的患者出现下消化道出血时,是否都需要对整个结肠进行可视化检查?
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本文引用的文献

1
Hereditary generalized juvenile polyposis associated with pulmonary arteriovenous malformation.与肺动静脉畸形相关的遗传性全身性幼年性息肉病。
Gastroenterology. 1980 Jun;78(6):1566-70.
2
Generalized juvenile polyposis with pulmonary arteriovenous malformations and hypertrophic osteoarthropathy.伴有肺动静脉畸形和肥厚性骨关节病的广义青少年息肉病。
AJR Am J Roentgenol. 1983 Oct;141(4):661-2. doi: 10.2214/ajr.141.4.661.
3
Association of hypertrophic osteoarthropathy with gastrointestinal polyposis.肥厚性骨关节病与胃肠道息肉病的关联。
遗传性出血性毛细血管扩张症合并广泛性幼年性息肉病。
Ulster Med J. 2001 Nov;70(2):145-8.
4
A survey of phenotypic features in juvenile polyposis.青少年息肉病的表型特征调查。
J Med Genet. 1998 Jun;35(6):476-81. doi: 10.1136/jmg.35.6.476.
AJR Am J Roentgenol. 1985 May;144(5):983-4. doi: 10.2214/ajr.144.5.983.
4
Clinical spectrum of hereditary hemorrhagic telangiectasia (Osler-Weber-Rendu disease).遗传性出血性毛细血管扩张症(奥斯勒-韦伯-伦杜病)的临床谱
Am J Med. 1987 May;82(5):989-97. doi: 10.1016/0002-9343(87)90162-8.
5
Juvenile polyposis--a precancerous condition.青少年息肉病——一种癌前病变状态。
Histopathology. 1988 Dec;13(6):619-30. doi: 10.1111/j.1365-2559.1988.tb02093.x.
6
Malignant potential of juvenile polyposis coli. Report of a case and review of the literature.幼年性结肠息肉病的恶性潜能。1例报告及文献复习。
Dis Colon Rectum. 1990 Nov;33(11):980-4. doi: 10.1007/BF02139111.
7
Polyposis syndromes--an update.息肉病综合征——最新进展
Curr Top Pathol. 1990;81:323-51. doi: 10.1007/978-3-642-74662-8_15.
8
Clinical and roentgen features of the intestinal polyposis syndromes.
Gastrointest Radiol. 1976;1(2):127-42. doi: 10.1007/BF02256355.