Department of Biochemistry, Uludag University Medical School, Bursa, Turkey.
Clin Biochem. 2012 Mar;45(4-5):298-302. doi: 10.1016/j.clinbiochem.2011.12.022. Epub 2012 Jan 10.
The aims of this study were to determine interrelationships between serum leptin, adiponectin and resistin, insulin-like growth factor-1 (IGF-1), total antioxidant capacity (TAC), non-esterified fatty acids (NEFA) and phospholipids concentrations in infants.
A cross-sectional study was conducted to assess serum levels of leptin, adiponectin, resistin, IGF-1, TAC, NEFA and phospholipids in 45 breast-fed infants enrolled at 4-30 days after birth.
Serum leptin and adiponectin concentrations were positively correlated. Serum resistin concentrations were inversely correlated to serum leptin and adiponectin concentrations. Serum TAC was positively correlated to serum leptin and adiponectin, and inversely to serum resistin concentrations. Serum adiponectin concentrations were positively related to serum NEFA and phospholipid concentrations. Serum resistin concentrations were inversely related to serum NEFA, and phospholipid concentrations.
These data show that circulatory levels of leptin, adiponectin and resistin are interrelated and they apparently interact with the anti-oxidant system of infants.
本研究旨在确定婴儿血清瘦素、脂联素和抵抗素、胰岛素样生长因子-1（IGF-1）、总抗氧化能力（TAC）、非酯化脂肪酸（NEFA）和磷脂浓度之间的相互关系。
进行了一项横断面研究，以评估 45 名母乳喂养的婴儿在出生后 4-30 天的血清瘦素、脂联素、抵抗素、IGF-1、TAC、NEFA 和磷脂水平。
血清瘦素和脂联素浓度呈正相关。血清抵抗素浓度与血清瘦素和脂联素浓度呈负相关。血清 TAC 与血清瘦素和脂联素呈正相关，与血清抵抗素浓度呈负相关。血清脂联素浓度与血清 NEFA 和磷脂浓度呈正相关。血清抵抗素浓度与血清 NEFA 和磷脂浓度呈负相关。
这些数据表明，循环中的瘦素、脂联素和抵抗素水平相互关联，它们显然与婴儿的抗氧化系统相互作用。
