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状态焦虑与年轻健康非裔美国人的心血管反应性有关。

State anxiety is associated with cardiovascular reactivity in young, healthy african americans.

作者信息

Pointer Mildred A, Yancey Sadiqa, Abou-Chacra Ranim, Petrusi Patricia, Waters Sandra J, McClelland Marilyn K

机构信息

Julius L. Chambers Biomedical/Biotechnology Research Institute, North Carolina Central University, Durham, NC 27707, USA.

出版信息

Int J Hypertens. 2012;2012:268013. doi: 10.1155/2012/268013. Epub 2012 Jan 3.

Abstract

Although several studies have shown that enhanced cardiovascular reactivity can predict hypertension development in African Americans, these findings have not been consistent among all studies examining reactivity and hypertension susceptibility. This inconsistency may be explained by the influence of anxiety (state and trait) on the blood pressure response to stress. Therefore, this study sought to determine whether anxiety is associated with blood pressure response to cold pressor (CP) and anger recall (AR) stress tests in young healthy African Americans. Modeling using state and trait anxiety revealed that state anxiety predicts systolic (SBP) and diastolic blood pressure DBP response to CP and AR (P ≤ 0.02). Interestingly, state anxiety predicted heart rate changes only to CP (P < 0.01; P = 0.3 for AR). Although trait anxiety was associated with SBP response to AR and not CP, it was not a significant predictor of reactivity in our models. We conclude that anxiety levels may contribute to the variable blood pressure response to acute stressors and, therefore, should be assessed when performing cardiovascular reactivity measures.

摘要

尽管多项研究表明,增强的心血管反应性可预测非裔美国人高血压的发展,但在所有研究反应性与高血压易感性的研究中,这些发现并不一致。这种不一致可能是由于焦虑(状态焦虑和特质焦虑)对压力引起的血压反应的影响。因此,本研究旨在确定焦虑是否与年轻健康非裔美国人对冷加压(CP)和愤怒回忆(AR)应激测试的血压反应相关。使用状态焦虑和特质焦虑进行建模显示,状态焦虑可预测对CP和AR的收缩压(SBP)和舒张压(DBP)反应(P≤0.02)。有趣的是,状态焦虑仅预测对CP的心率变化(P<0.01;对AR为P = 0.3)。尽管特质焦虑与对AR而非CP的SBP反应相关,但在我们的模型中它并不是反应性的显著预测因素。我们得出结论,焦虑水平可能导致对急性应激源的血压反应存在差异,因此,在进行心血管反应性测量时应评估焦虑水平。

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本文引用的文献

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Function and structure of resistance vessels in black and white people.黑人和白人的阻力血管的功能和结构。
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Stress reactivity and its association with increased cardiovascular risk: a role for the sympathetic nervous system?
Hypertension. 2010 Jun;55(6):e20; author reply e21. doi: 10.1161/HYPERTENSIONAHA.110.153841. Epub 2010 May 3.
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Chronic psychosocial stress and hypertension.慢性心理社会应激与高血压。
Curr Hypertens Rep. 2010 Feb;12(1):10-6. doi: 10.1007/s11906-009-0084-8.
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Psychosocial and biobehavioral factors and their interplay in coronary heart disease.
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