Tugay Nazan, Saricaoglu Fatma, Satilmis Tulin, Alpar Ulku, Akarcali Inci, Citaker Seyit, Tugay Umut, Atilla Bulent, Tokgozoglu Mazhar
Department of Physiotherapy and Rehabilitation, (Formerly from the School of Physical Therapy and Rehabilitation, Hacettepe University) Mugla School of Health, Mugla 48000, Turkey. Tel. +90 (252) 2141243. Fax. +90 (252) 2124755. E-mail:
Neurosciences (Riyadh). 2006 Jul;11(3):175-9.
To investigate the efficacy of single injection femoral nerve block (FNB) on the independence level in functional activities in the early postoperative period in patients with total knee arthroplasty (TKA).
We conducted this prospective, randomized, blinded trial in the Department of Orthopedics and Traumatology, Hacettepe University Hospital Ankara, Turkey, between June 2003 and April 2004. Twenty-three patients scheduled for elective TKA were randomly divided into 3 groups. Group I received preemptive single injection FNB, group II received postoperative single injection FNB, and group III served as a control group. Intravenous morphine patient controlled analgesia (PCA) was used following surgery in all groups. Morphine dose and pain score defined by the visual analog scale (VAS) were recorded postoperatively at the 15th minute, 30th minute, 1st, 4th, 6th, 12th, 24th, and 48th hours. A standard rehabilitation protocol was applied for all patients. The independence level in functional activities was assessed during the first 2 postoperative days and at discharge with the Iowa Level of Assistance Scale (ILAS) and the Iowa Ambulation Speed Scale (IASS). Physical therapists that enrolled in the study were blinded to the groups.
Pain scores were significantly different between the groups (p<0.05). The preemptive and postoperative FNB group`s VAS scores were both significantly lower than the control group (p<0.05). However, there was no significant difference in VAS scores between preemptive and postoperative FNB groups (p>0.05). There was no statistically significant difference between the groups in any of the functional scores in the first 2 postoperative days, and at discharge (p>0.05).
Single injection FNB provided effective analgesia in patients undergoing TKA. However, the independence level in functional activities in the early postoperative period was not influenced by the analgesia method.
探讨单次注射股神经阻滞(FNB)对全膝关节置换术(TKA)患者术后早期功能活动独立水平的疗效。
2003年6月至2004年4月,我们在土耳其安卡拉哈杰泰佩大学医院骨科进行了这项前瞻性、随机、双盲试验。23例择期行TKA的患者被随机分为3组。第一组接受术前单次注射FNB,第二组接受术后单次注射FNB,第三组作为对照组。所有组术后均采用静脉吗啡患者自控镇痛(PCA)。术后第15分钟、30分钟、1小时、4小时、6小时、12小时、24小时和48小时记录吗啡剂量和视觉模拟量表(VAS)定义的疼痛评分。所有患者均采用标准康复方案。术后前两天及出院时,采用爱荷华州协助水平量表(ILAS)和爱荷华州步行速度量表(IASS)评估功能活动的独立水平。参与研究的物理治疗师对分组情况不知情。
各组间疼痛评分有显著差异(p<0.05)。术前和术后FNB组的VAS评分均显著低于对照组(p<0.05)。然而,术前和术后FNB组的VAS评分之间无显著差异(p>0.05)。术后前两天及出院时,各组在任何功能评分上均无统计学显著差异(p>0.05)。
单次注射FNB为TKA患者提供了有效的镇痛。然而,术后早期功能活动的独立水平不受镇痛方法的影响。