State Key Laboratory of Virology, College of Chemistry and Molecular Sciences, Wuhan University, 430072 Wuhan, PR China.
Chemistry. 2012 Feb 20;18(8):2221-5. doi: 10.1002/chem.201103918. Epub 2012 Jan 20.
Make it unique! A mixed-ligand system of Pd/Synphos/Xantphos promotes effective C-N coupling in the synthesis of various N-arylaminotriazole and N-arylaminopurine nucleoside analogues. This catalytic system is strikingly powerful and efficient, allowing for unparalleled substrate scope and high product yields as well as promotion of C-Cl bond activation for C-N coupling (see scheme).
使其独一无二！Pd/Synphos/Xantphos 的混合配体体系在各种 N-芳基氨三唑和 N-芳基氨基嘌呤核苷类似物的合成中促进有效的 C-N 偶联。该催化体系具有惊人的强大和高效性，允许无与伦比的底物范围和高产物收率，并促进 C-Cl 键活化以进行 C-N 偶联（见方案）。
