Dapp U, Fertmann R, Anders J, Schmidt S, Pröfener F, Deneke C, Minder C, Hasford J, von Renteln-Kruse W
Forschungsabteilung, Albertinen-Haus, Zentrum für Geriatrie und Gerontologie, Wissenschaftliche Einrichtung an der Universität Hamburg, Sellhopsweg 18-22, 22459, Hamburg, Deutschland.
Z Gerontol Geriatr. 2011 Dec;44 Suppl 2:55-72. doi: 10.1007/s00391-011-0244-8.
The interactions between rising life expectancy, morbidity and development of disability warrant interdisciplinary research on functional disability, health promotion and prevention as well as healthcare provision for older people. Therefore, the interdisciplinary LUCAS (Longitudinal Urban Cohort Ageing Study) research consortium of university and non-university institutions was established and is coordinated by the research department of the Albertinen-Haus at the University of Hamburg. The aim is to study particular aspects of functional competence, the changes with ageing, to detect pre-clinical signs of functional decline and to address questions on how to maintain functional competence and to prevent adverse outcomes. The research questions have their origin in problems of practical healthcare provision in the different settings of communities, hospitals and nursing homes. The articles of LUCAS subprojects report selected results from the first project phase (2007-2010) which was funded by the German Federal Ministry of Education and Research (BMBF) (Research program"Health in the elderly").).
The LUCAS subprojects 1-7 applied a true cohort study design with embedded randomized controlled intervention studies and cross-sectional studies for comparative purposes and to prepare intervention studies to be performed in the second project phase.
Results from the first project phase provided new instruments to screen and to assess functional competence in older people (population-based screening). In the second project phase these will be evaluated according to practicability and usefulness. Furthermore, parts of the results will be used by the health reporting system in Hamburg and for intervention studies performed by LUCAS subprojects during the second project phase (LUCAS II).
预期寿命的增长、发病率与残疾发展之间的相互作用需要开展关于功能残疾、健康促进与预防以及老年人医疗保健服务的跨学科研究。因此，由大学和非大学机构组成的跨学科LUCAS（纵向城市队列老龄化研究）研究联盟得以成立，并由汉堡大学阿尔贝蒂宁之家的研究部门协调。其目的是研究功能能力的特定方面、随年龄增长的变化，检测功能衰退的临床前迹象，并解决如何维持功能能力以及预防不良后果的问题。这些研究问题源于社区、医院和养老院等不同环境中实际医疗保健服务的问题。LUCAS子项目的文章报告了第一个项目阶段（2007 - 2010年）的部分选定结果，该阶段由德国联邦教育与研究部（BMBF）资助（研究项目“老年人健康”）。
LUCAS子项目1 - 7采用了真实队列研究设计，并嵌入随机对照干预研究和横断面研究，用于比较目的以及为在第二个项目阶段进行的干预研究做准备。
第一个项目阶段的结果提供了新的工具，用于筛查和评估老年人的功能能力（基于人群的筛查）。在第二个项目阶段，将根据实用性和有效性对这些工具进行评估。此外，部分结果将被汉堡的健康报告系统使用，并用于LUCAS子项目在第二个项目阶段（LUCAS II）进行的干预研究。
