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社区居住老年人健康状况、虚弱程度、护理及死亡率变化的长期预测——纵向城市队列老龄化研究(LUCAS)的结果

Long-term prediction of changes in health status, frailty, nursing care and mortality in community-dwelling senior citizens—results from the Longitudinal Urban Cohort Ageing Study (LUCAS).

作者信息

Dapp Ulrike, Minder Christoph E, Anders Jennifer, Golgert Stefan, von Renteln-Kruse Wolfgang

机构信息

Albertinen-Haus Geriatrics Center, Scientific Department, University of Hamburg, Sellhopsweg 18-22, D-22459 Hamburg, Germany.

出版信息

BMC Geriatr. 2014 Dec 19;14:141. doi: 10.1186/1471-2318-14-141.

Abstract

BACKGROUND

The detection of incipient functional decline in elderly persons is not an easy task. Here, we propose the self-reporting Functional Ability Index (FA index) suitable to screen functional competence in senior citizens in the community setting. Its prognostic validity was investigated in the Longitudinal Urban Cohort Ageing Study (LUCAS).

METHODS

This index is based equally on both, resources and risks/functional restrictions which precede ADL limitations. Since 2001, the FA index was tested in the LUCAS cohort without any ADL restrictions at baseline (n = 1,679), and followed up by repeated questionnaires in Hamburg, Germany.

RESULTS

Applying the index, 1,022 LUCAS participants were initially classified as Robust (60.9%), 220 as postRobust (13.1%), 172 as preFrail (10.2%) and 265 as Frail (15.8%). This classification correlated with self-reported health, chronic pain and depressive mood (rank correlations 0.42, 0.26, 0.21; all p < .0001). Survival analyses showed significant differences between these classes as determined by the FA index: the initially Robust survived longest, the Frail shortest (p < .0001). Analyses of the time to need of nursing care revealed similar results. Significant differences persisted after adjustment for age, sex and self-reported health.

CONCLUSIONS

Disability free lifetime and its development over time are important topics in public health. In this context, the FA index presented here provides answers to two questions. First, how to screen the heterogeneous population of community-dwelling senior citizens, i.e. for their functional ability/competence, and second, how far away they are from disability/dependency. Furthermore, the index provides a tool to address the urgent question whether incipient functional decline/incipient frailty can be recognized early to be influenced positively. The FA index predicted change in functional status, future need of nursing care, and mortality in an unselected population of community-dwelling seniors. It implies an operational specification of the classification into Robust, postRobust, preFrail and Frail. Based on a self-administered questionnaire, the FA index allows easy screening of elderly persons for declining functional competence. Thereby, incipient functional decline is recognized, e.g. in GPs' practices and senior community health centers, to initiate early appropriate preventive action.

摘要

背景

检测老年人早期功能衰退并非易事。在此,我们提出了适用于在社区环境中筛查老年人功能能力的自我报告功能能力指数(FA指数)。在纵向城市队列老龄化研究(LUCAS)中对其预后有效性进行了调查。

方法

该指数同样基于日常生活活动(ADL)受限之前的资源以及风险/功能限制。自2001年以来,FA指数在LUCAS队列中进行了测试,该队列在基线时无任何ADL限制(n = 1679),并在德国汉堡通过重复问卷调查进行随访。

结果

应用该指数,1022名LUCAS参与者最初被归类为强健型(60.9%),220名被归类为后强健型(13.1%),172名被归类为虚弱前期(10.2%),265名被归类为虚弱型(15.8%)。这种分类与自我报告的健康状况、慢性疼痛和抑郁情绪相关(等级相关性分别为0.42、0.26、0.21;所有p <.0001)。生存分析表明,FA指数确定的这些类别之间存在显著差异:最初强健型存活时间最长,虚弱型最短(p <.0001)。对需要护理时间的分析得出了类似结果。在对年龄、性别和自我报告的健康状况进行调整后,显著差异仍然存在。

结论

无残疾生存期及其随时间的变化是公共卫生中的重要课题。在此背景下,本文提出的FA指数回答了两个问题。第一,如何筛查社区居住老年人的异质性群体,即他们的功能能力/胜任力,第二,他们离残疾/依赖状态还有多远。此外,该指数提供了一种工具,以解决能否早期识别早期功能衰退/早期虚弱并对其产生积极影响这一紧迫问题。FA指数预测了社区居住老年人未选择人群的功能状态变化、未来护理需求和死亡率。它意味着对强健、后强健、虚弱前期和虚弱分类的操作规范。基于自我管理的问卷,FA指数便于对老年人功能能力下降进行筛查。从而在例如全科医生诊所和社区老年健康中心识别早期功能衰退,以便启动早期适当的预防行动。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/604e/4289576/5354150c00cb/12877_2014_1074_Fig1_HTML.jpg

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