von Renteln-Kruse W, Dapp U, Anders J, Pröfener F, Schmidt S, Deneke C, Fertmann R, Hasford J, Minder C
Forschungsabteilung und Medizinisch-Geriatrische Klinik, Albertinen-Haus Zentrum für Geriatrie und Gerontologie, Wissenschaftliche Einrichtung an der Universität Hamburg, Sellhopsweg 18-22, 22459, Hamburg, Deutschland.
Z Gerontol Geriatr. 2011 Aug;44(4):250-5. doi: 10.1007/s00391-011-0224-z.
Decline in functional competence is a major determinant of older persons' needs, the development of dependency, use of care, clinical outcome and mortality. The interactions between rising life expectancy and changes in morbidity and disability warrant interdisciplinary research on functional disability, health promotion and prevention. The LUCAS (Longitudinal Urban Cohort Ageing Study) research consortium was established to study particular aspects of functional competence, its changes with ageing, to detect preclinical signs of functional decline, and to address questions on how to maintain functional competence and to prevent adverse outcome. The questions originate from problems encountered in practical health care provision in different settings, i.e. community, hospital and nursing home.
The subprojects apply a longitudinal cohort follow-up study, an embedded randomised controlled intervention, cross-sectional comparative, and prospective intervention studies.
The results will provide instruments to screen for preclinical signs of functional decline and concrete recommendations to sustain independence and prevent adverse outcomes in older age in daily practice.
功能能力下降是老年人需求、依赖发展、护理使用、临床结局和死亡率的主要决定因素。预期寿命上升与发病率和残疾率变化之间的相互作用需要对功能残疾、健康促进和预防进行跨学科研究。成立LUCAS(纵向城市队列老龄化研究)研究联盟是为了研究功能能力的特定方面、其随年龄的变化、检测功能下降的临床前体征,并解决如何维持功能能力和预防不良结局的问题。这些问题源于在不同环境(即社区、医院和养老院)的实际医疗保健提供中遇到的问题。
子项目采用纵向队列随访研究、嵌入式随机对照干预、横断面比较和前瞻性干预研究。
研究结果将提供筛查功能下降临床前体征的工具,并提供在日常实践中维持老年人独立性和预防不良结局的具体建议。