Experimental and Clinical Research Center, a joint cooperation between the Charité Medical Faculty and the Max-Delbrück Center for Molecular Medicine, Charité University Clinic, Berlin, Germany.
Eur Eat Disord Rev. 2012 Sep;20(5):400-5. doi: 10.1002/erv.1166. Epub 2012 Jan 24.
The utility of bioelectrical impedance analysis (BIA) in patients with anorexia nervosa (AN) is imperfectly defined. Furthermore, any advantage accrued by BIA with vector analysis (BIVA) is unknown.
We conducted a retrospective analysis of 57 women with AN admitted to our service who underwent BIA and BIVA. Twenty-seven women were observed during short-term (3 weeks) and 13 women during longer-term (3 months) weight gain.
Bioelectrical impedance analysis produced implausible results in 47% of the patients. BIVA demonstrated low body cell mass and highly variable extracellular water (ECW) volume, ranging from volume contraction to volume expansion on admission and during treatment. BIVA suggested that short-term weight gain predominantly consisted of ECW volume, whereas longer-term weight gain resulted in increased hydrated body cell mass.
Conventional BIA has little utility in these patients. However, BIVA could be a suitable alternative in the medical management reflecting ECW volume changes and later genuine tissue mass increases.
生物电阻抗分析（BIA）在神经性厌食症（AN）患者中的应用价值尚未明确。此外，向量分析（BIVA）的 BIA 是否具有优势尚不清楚。
我们对我院收治的 57 例接受 BIA 和 BIVA 的 AN 女性患者进行了回顾性分析。其中 27 例在短期（3 周）体重增加期间接受观察，13 例在长期（3 个月）体重增加期间接受观察。
BIA 在 47%的患者中产生了不可信的结果。BIVA 显示低体细胞量和高度可变的细胞外液（ECW）体积，入院时和治疗期间从 ECW 体积收缩到扩张变化范围。BIVA 提示短期体重增加主要由 ECW 体积组成，而长期体重增加导致水合体细胞量增加。
传统 BIA 在这些患者中的应用价值有限。然而，BIVA 可能是一种合适的替代方法，可反映 ECW 体积变化，以及后期真正的组织质量增加。
