Dos Reis Tâmara Oliveira, de Magalhães Oliveira Fernanda, Kattah Fabiana Martins, Pena Natalia Fenner, Soares Maria Marta Sarquis, da Gama Torres Henrique Oswaldo
Adult Health Post-Graduate Program, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Núcleo de Investigação de Anorexia E Bulimia (NIAB), Hospital das Clinicas, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
J Eat Disord. 2022 Nov 16;10(1):167. doi: 10.1186/s40337-022-00702-x.
In Anorexia Nervosa (AN) recovery, body mass index (BMI) may not reflect body composition. To investigate recovery, bioelectrical impedance (BIA) parameters and energy expenditure were investigated in patients with active and recovering AN, with emphasis on phase angle (PA), a BIA parameter.
BMI, PA, indirect BIA parameters (fat free mass, fat mass, total body water, fat free mass index, fat mass index) and resting metabolic rate (RMR) were obtained. Data from subjects distributed to active AN (ANact, n = 9), recovered AN (ANrec, n = 9) and healthy individuals (HI) (n = 16) were compared employing univariate methods and ordinal logistic regression.
In univariate comparison, the BMI would not distinguish recovered individuals; this distinction was observed for the PA (p = < 0,001). PA showed a good capacity to discriminate, between ANrec and HI (AUC = 0.792; CI = 0.564- 1.000; p = 0.017). In 2 models of ordinal logistic regression PA (OR = 0.123; 95% CI 0.030; 0.503 and OR = 0.091; 95% CI 0.016; 0.528) remained as a significant independent variable, indicating that increases in PA are related to higher probabilities of moving from ANact, to ANrec and to HI group. Bivariate regression indicated the presence of a relationship between PA and (R2 = 0.266, p = 0.002).
Changes in body composition and energy expenditure were observed in recovered anorexics with normal BMI. PA can play an important role in the assessment of recovering anorexic patients.
在神经性厌食症（AN）的康复过程中，体重指数（BMI）可能无法反映身体成分。为了研究康复情况，我们对处于活动期和康复期的AN患者的生物电阻抗（BIA）参数和能量消耗进行了研究，重点关注BIA参数相角（PA）。
获取BMI、PA、间接BIA参数（去脂体重、脂肪量、总体水、去脂体重指数、脂肪量指数）和静息代谢率（RMR）。采用单变量方法和有序逻辑回归对分配到活动期AN（ANact，n = 9）、康复期AN（ANrec，n = 9）和健康个体（HI）（n = 16）的受试者数据进行比较。
在单变量比较中，BMI无法区分康复个体；而PA能观察到这种差异（p = <0.001）。PA显示出良好的区分能力，可区分ANrec和HI（AUC = 0.792；CI = 0.564 - 1.000；p = 0.017）。在两个有序逻辑回归模型中，PA（OR = 0.123；95% CI 0.030；0.503和OR = 0.091；95% CI 0.016；0.528）仍然是一个显著的独立变量，表明PA的增加与从ANact转变为ANrec以及HI组的更高概率相关。双变量回归表明PA与（R2 = 0.266，p = 0.002）之间存在关系。
在BMI正常的康复厌食症患者中观察到了身体成分和能量消耗的变化。PA在评估康复的厌食症患者中可发挥重要作用。
