疲劳测量指标与类风湿关节炎和骨关节炎患者健康相关生活质量的相关性。
Association Between Measures of Fatigue and Health-Related Quality of Life in Rheumatoid Arthritis and Osteoarthritis.
机构信息
1 Bone and Joint Research, Kolling Institute, University of Sydney, Sydney, New South Wales, Australia 2 Centre for National Research on Disability, University of Queensland, Brisbane, Queensland, Australia 3 Health Sciences, University of Queensland, Brisbane, Queensland, Australia.
出版信息
Patient. 2008 Apr 1;1(2):97-104. doi: 10.2165/01312067-200801020-00005.
OBJECTIVE
To assess the relationship between fatigue and health-related quality of life (HR-QOL) among people with osteoarthritis (OA) and rheumatoid arthritis (RA).
METHODS
Community-dwelling people with OA, and OA patients on the waiting list for joint replacement surgery, were recruited. RA patients were recruited from rheumatologists' public and private outpatient clinics. Respondents completed a questionnaire containing demographic detail, the Fatigue Severity Scale (FSS), the Multidimensional Assessment of Fatigue (MAF), the SF-36, Western Ontario and McMaster Universities Osteoarthritis Index, and the Health Assessment Questionnaire (HAQ).
RESULTS
There were 137 OA and 52 RA respondents. Neither age nor sex was significantly associated with fatigue for OA or RA. The mean FSS score was 3.36 for RA and 3.63 for OA. Fifty percent of respondents with RA and 58% of those with OA met the FSS >3 cut-point for fatigue. Mean MAF Global Fatigue Index was 20.8 for OA and 20.1 for RA. Correlations between health status and fatigue indicated that for both OA and RA those with greater fatigue reported worse health status.
CONCLUSIONS
Few studies have measured the impact of fatigue among respondents with OA, despite it affecting a large proportion of the population. Fatigue was significantly correlated with poorer HR-QOL among OA respondents, suggesting that fatigue is a significant issue in OA as well as RA.
目的
评估骨关节炎（OA）和类风湿关节炎（RA）患者的疲劳与健康相关生活质量（HR-QOL）之间的关系。
方法
招募社区居住的 OA 患者，以及等待关节置换手术的 OA 患者。RA 患者从风湿病学家的公共和私人门诊中招募。受访者完成了一份问卷，其中包含人口统计细节、疲劳严重程度量表（FSS）、多维疲劳评估（MAF）、SF-36、安大略西部和麦克马斯特大学骨关节炎指数以及健康评估问卷（HAQ）。
结果
有 137 名 OA 和 52 名 RA 受访者。年龄和性别均与 OA 或 RA 的疲劳无显著相关性。RA 的平均 FSS 得分为 3.36，OA 的平均 FSS 得分为 3.63。50%的 RA 受访者和 58%的 OA 受访者的 FSS ＞3 得分表明有疲劳症状。OA 的平均 MAF 全球疲劳指数为 20.8，RA 的平均 MAF 全球疲劳指数为 20.1。健康状况与疲劳之间的相关性表明，OA 和 RA 患者中，疲劳程度越高，健康状况越差。
结论
尽管疲劳影响了很大一部分人群，但很少有研究测量 OA 患者的疲劳影响。OA 受访者的疲劳与较差的 HR-QOL 显著相关，这表明疲劳是 OA 和 RA 中的一个重要问题。
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