Jaillon Franck, Makita Shuichi, Yasuno Yoshiaki
Computational Optics Group, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8573, Japan.
Opt Express. 2012 Jan 2;20(1):385-96. doi: 10.1364/OE.20.000385.
In this study, we present dual-beam Doppler optical coherence angiography with variable beam separation. Altering beam distance, independently of the scanning protocol, provides a flexible way to select the velocity range of detectable blood flow. This system utilized a one-micrometer wavelength light source to visualize deep into the posterior eye, i.e., the choroid. Two-dimensional choroidal vasculature maps of a human subject acquired with different beam separations, and hence with several velocity ranges, are presented. Combining these maps yields a semi-quantitative visualization of axial velocity of the choroidal circulation. The proposed technique may be useful for identifying choroidal abnormalities that occur in pathological conditions of the eye.
在本研究中，我们展示了具有可变光束间距的双光束多普勒光学相干血管造影术。独立于扫描协议改变光束距离，提供了一种灵活的方式来选择可检测血流的速度范围。该系统利用一微米波长的光源深入可视化眼后段，即脉络膜。展示了用不同光束间距（从而具有多个速度范围）获取的人类受试者的二维脉络膜血管图。将这些图结合起来可实现脉络膜循环轴向速度的半定量可视化。所提出的技术可能有助于识别眼部病理状况下出现的脉络膜异常。
