Hsieh Bao-Yu, Chen Sung-Liang, Ling Tao, Guo L Jay, Li Pai-Chi
Graduate Institute of Biomedical Electronics and Bioinformatics, National Taiwan University, Taipei, Taiwan.
Opt Express. 2012 Jan 16;20(2):1588-96. doi: 10.1364/OE.20.001588.
We propose a new scanhead design for combined ultrasound (US)/photoacoustic (PA) imaging that can be applied to dual-modality microscopy and biomedical imaging. Both imaging modalities employ the optical generation and detection of acoustic waves. The scanhead consists of an optical fiber with an axicon tip for excitation, and a microring for acoustic detection. No conventional piezoelectric device is needed, and the cost of the design makes it suitable for one-time, disposable use. Furthermore, a single laser pulse is employed to generate both US and PA signals. A subband imaging method can be applied to the receiver to enhance the contrast between the US and PA signals. Phantom data demonstrate the feasibility of this approach.
我们提出了一种用于超声(US)/光声(PA)联合成像的新型扫描头设计,该设计可应用于双模态显微镜和生物医学成像。两种成像模态均采用声波的光学产生和检测。扫描头由一根带有用于激发的轴棱锥尖端的光纤和一个用于声学检测的微环组成。无需传统的压电装置,且该设计成本使其适用于一次性使用。此外,使用单个激光脉冲来产生超声和光声信号。可以将子带成像方法应用于接收器以增强超声和光声信号之间的对比度。仿体数据证明了该方法的可行性。