Unitat de Rinologia i Clínica de l'Olfacte, Servei d'Otorinolaringologia, Hospital Clínic i Universitari, IDIBAPS, Barcelona, Catalunya, Spain.
Curr Allergy Asthma Rep. 2012 Apr;12(2):144-53. doi: 10.1007/s11882-012-0247-6.
Chronic rhinosinusitis with nasal polyps (CRSwNP) is a chronic inflammatory disease of the nasal and paranasal sinus mucosa that, despite differing hypotheses regarding its cause, remains poorly understood. Major symptoms are nasal congestion or blockage, loss of smell, rhinorrhea, postnasal drip, and facial pain or pressure. Among the objectives of CRSwNP management are to eradicate nasal polyps from nasal and sinusal cavities, eliminate symptoms, and prevent recurrences. Corticosteroids are the mainstay of treatment and are the most effective drugs for treating CRSwNP. Other potential treatments are nasal saline irrigation and antihistamines (in allergic conditions). Endoscopic sinus surgery is recommended when medical treatment fails. After surgery, medical treatment, including nasal and oral corticosteroids, is recommended.
伴有鼻息肉的慢性鼻-鼻窦炎（CRSwNP）是一种慢性鼻和鼻旁窦黏膜炎症性疾病，尽管其病因假说不同，但仍知之甚少。主要症状是鼻塞或阻塞、嗅觉丧失、流涕、后鼻滴注和面部疼痛或压力。CRSwNP 管理的目标之一是从鼻腔和鼻窦腔中根除鼻息肉，消除症状并预防复发。皮质类固醇是治疗的主要药物，也是治疗 CRSwNP 最有效的药物。其他潜在的治疗方法包括鼻腔盐水冲洗和抗组胺药（在过敏情况下）。当药物治疗失败时，建议进行内镜鼻窦手术。手术后，建议进行包括鼻内和口服皮质类固醇在内的药物治疗。
