Rubio C A, Kock Y, Stormby N, Porwit A
Department of Pathology, Karolinska Institute, Stockholm, Sweden.
Gynecol Oncol. 1990 Nov;39(2):167-70. doi: 10.1016/0090-8258(90)90426-l.
A model system of exfoliated normal human cervicovaginal squamous cells, exfoliated rodent tumor cells, and acellular, viscous, mucuslike material was used to investigate cell deposition on smear preparations made with three different instruments: plastic spatulas, wooden spatulas, and brush-tipped collectors. The total number of exfoliated cells and the total number of tumor cells present within the randomly distributed holes were then recorded for 41 smear preparations. For smears done with the brush, a total of 47,146 exfoliated cells were recorded; with wooden spatulas, 4517 cells; and with plastic spatulas, 7648 cells. When the brush was used, 6905 tumor cells were recorded. When wooden or plastic spatulas were applied, 563 and 1132 tumor cells were found, respectively. Thus, the brush yielded 12.2 and 6.1 times more tumor cells than plastic and wooden spatulas, respectively.
使用一个由脱落的正常人类宫颈阴道鳞状细胞、脱落的啮齿动物肿瘤细胞以及无细胞的、粘性的、粘液样物质组成的模型系统，来研究细胞在使用三种不同器械制作的涂片标本上的沉积情况：塑料刮片、木质刮片和刷头采集器。然后记录了41个涂片标本中随机分布的孔内脱落细胞的总数和肿瘤细胞的总数。对于用刷子制作的涂片，记录到总共47146个脱落细胞；用木质刮片制作的涂片有4517个细胞；用塑料刮片制作的涂片有7648个细胞。使用刷子时，记录到6905个肿瘤细胞。使用木质或塑料刮片时，分别发现563个和1132个肿瘤细胞。因此，刷子产生的肿瘤细胞分别是塑料刮片和木质刮片的12.2倍和6.1倍。
