肯尼亚西部一家区级医院为患有宫颈上皮内瘤变的女性提供冷冻治疗服务的报告。
Report on a cryotherapy service for women with cervical intraepithelial neoplasia in a district hospital in western Kenya.
作者信息
Lewis K D C, Sellors J W, Dawa A, Tsu V D, Kidula N A
机构信息
Reproductive Health Program, PATH, Seattle, USA.
出版信息
Afr Health Sci. 2011 Sep;11(3):370-6.
BACKGROUND
In low-resource settings, cryotherapy can be cost-effective, affordable, and a first-line treatment for cervical intraepithelial neplasia (CIN) of any grade.
OBJECTIVES
To report the acceptability, safety and effectiveness of cryotherapy for women with cervical intraepithelial neoplasia (CIN) in Western Kenya.
METHODS
Visual inspection with acetic acid (VIA)-positive women and those suspected of having cervical cancer based on an initial evaluation at a primary health facility were referred to the district hospital for colposcopy and additional evaluation using visual inspection with Lugol's iodine (VILI) and/or visual inspection with acetic acid and magnification (VIAM). Cryotherapy was offered immediately to women diagnosed with appropriate CIN lesions based on colposcopy or after waiting for a confirmatory cervical biopsy and a follow up visit occurred one year later.
RESULTS
Ninety one 91 women 30 to 39 years of age had CIN appropriate for cryotherapy. Approximately 36% (24/67) were due for their 1 year follow up visit and 20 of 24 (83.3%) attended. Complete data were available for 18 of 20 (90%) and 13 (72.2%) had no sign of CIN. No serious adverse events were reported 1 to 3 months after cryotherapy. All respondents reported that the treatment experience was acceptable.
CONCLUSIONS
Cryotherapy was acceptable, safe and effective.
背景
在资源匮乏地区，冷冻疗法具有成本效益、价格可承受，可作为任何级别的宫颈上皮内瘤变（CIN）的一线治疗方法。
目的
报告肯尼亚西部宫颈上皮内瘤变（CIN）女性接受冷冻疗法的可接受性、安全性和有效性。
方法
在初级卫生机构进行初步评估时，醋酸肉眼观察（VIA）呈阳性的女性以及疑似患有宫颈癌的女性被转诊至地区医院进行阴道镜检查，并使用卢戈氏碘液肉眼观察（VILI）和/或醋酸放大肉眼观察（VIAM）进行进一步评估。根据阴道镜检查结果，对诊断为适当CIN病变的女性立即进行冷冻治疗，或在等待宫颈活检确诊后进行治疗，一年后进行随访。
结果
91名年龄在30至39岁之间的女性患有适合冷冻治疗的CIN。约36%（24/67）的患者应进行1年随访，其中24人中有20人（83.3%）前来就诊。20名患者中有18人（90%）获得了完整数据，其中13人（72.2%）无CIN迹象。冷冻治疗后1至3个月未报告严重不良事件。所有受访者均表示治疗体验可以接受。
结论
冷冻疗法是可接受、安全且有效的。
Zotero 插件