Department of Oral and Maxillofacial Surgery, Division of Cervico-Gnathostomatology, Graduate School of Biomedical Sciences, Hiroshima University, Kasumi 1-2-3, Minami-ku, Hiroshima 734-8553, Japan.
Dent Mater J. 2012 Feb 3;31(1):54-60. doi: 10.4012/dmj.2011-089. Epub 2012 Jan 21.
The aim of this study was to evaluate the clinical behavior and the histological aspects of interconnected porous hydroxyapatite ceramics (IP-CHA) in maxillary sinus floor augmentation procedures. A 59-year-old female patient received one-stage implant integration with right maxillary sinus floor augmentation with mixture grafts from the cortical bone and IP-CHA. Implant stability of each fixture increased at 9 months after fixture installation compared with the first operation and adequate fixation of each fixture could be obtained. Histological analysis revealed there was new bone formation in the majority of pores of IP-CHA. Moreover, on a panoramic radiograph taken at 33 months the mixture grafts were distinctly observed as a radiopacity in the right sinus cavity, and marked absorption of mixture grafts was not found. Our results suggest that IP-CHA has the potential to provide a major scaffold for osteoprogenitor cells and is a useful grafting material for maxillary sinus augmentation.
本研究旨在评估相互连通多孔羟基磷灰石陶瓷（IP-CHA）在上颌窦底提升术中的临床行为和组织学方面。一位 59 岁女性患者接受了单侧上颌窦底提升术与皮质骨和 IP-CHA 混合物移植物同期植入，实现了一期种植体整合。与初次手术相比，植入物安装后 9 个月每个固定装置的稳定性都有所增加，并且可以获得每个固定装置的适当固定。组织学分析显示，在大多数 IP-CHA 孔隙中形成了新骨。此外，在 33 个月时拍摄的全景片上，右侧窦腔内明显观察到混合物移植物的放射性不透明度，且未发现混合物移植物明显吸收。我们的结果表明，IP-CHA 有可能为成骨细胞提供主要的支架，是上颌窦提升的一种有用的植骨材料。
