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欧洲布鲁氏菌病的跨境分子溯源。

Cross-border molecular tracing of brucellosis in Europe.

机构信息

Institute of Bacterial Infections and Zoonoses, Friedrich Loeffler Institute, Jena, Germany.

出版信息

Comp Immunol Microbiol Infect Dis. 2012 Mar;35(2):181-5. doi: 10.1016/j.cimid.2011.12.012. Epub 2012 Jan 23.

Abstract

To assess the general impact of endemic countries on the re-emergence of brucellosis in non-endemic regions of the European Union, the genetic fingerprints of Brucella melitensis strains imported to Germany were compared to ovine strains from Turkey in a molecular epidemiological study. Genotyping of 66 Brucella strains (based on Multiple Locus of Variable number of tandem repeats Analysis) isolated from German travellers and Turkish immigrants living in Germany revealed epidemiological concordance with 20 sheep isolates originating from Eastern Anatolia, Turkey. In summary, cross-border molecular tracing confirmed brucellosis being a zoonosis of concern for European public health.

摘要

为了评估地方性流行国家对欧盟非地方性流行地区布鲁氏菌病重新出现的总体影响,在分子流行病学研究中,比较了德国进口的马耳他布鲁氏菌菌株与土耳其绵羊菌株的遗传指纹。对 66 株从德国旅行者和生活在德国的土耳其移民中分离的布鲁氏菌菌株(基于多位点可变数串联重复分析)进行基因分型,结果与来自土耳其东安纳托利亚的 20 株绵羊分离株具有流行病学一致性。总之,跨境分子追踪证实了布鲁氏菌病是对欧洲公共卫生的一种关注的人畜共患病。

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