Knight Cancer Institute, Oregon Health and Science University, Portland, OR 97239, USA.
Sci Transl Med. 2012 Jan 25;4(118):118cm2. doi: 10.1126/scitranslmed.3002951.
Clinical research is burdened by inefficiencies and complexities, with a poor record of trial completion, none of which is desirable. The Clinical and Translational Science Award (CTSA) Consortium, including more than 60 clinical research institutions, supports a unified national effort to become, in effect, a virtual national laboratory designed to identify, implement, evaluate, and extend process improvements across all parts of clinical research, from conception to completion. If adequately supported by academic health centers, industry, and funding agencies, the Consortium could become a test bed for improvements that can dramatically reduce wasteful complexity, thus increasing the likelihood of clinical trial completion.
临床研究受到效率低下和复杂性的困扰，试验完成情况不佳，这些都不理想。临床和转化科学奖（CTSA）联盟包括 60 多个临床研究机构，支持统一的国家努力，实际上成为一个虚拟的国家实验室，旨在确定、实施、评估和扩展临床研究各个方面的流程改进，从概念到完成。如果得到学术医疗中心、行业和资助机构的充分支持，该联盟可以成为改进的试验基地，可以显著减少浪费性的复杂性，从而增加临床试验完成的可能性。
