The School of Nursing, The University of Texas at Austin, Austin, TX 78701-1499, USA.
Arch Womens Ment Health. 2012 Feb;15(1):57-67. doi: 10.1007/s00737-012-0258-2. Epub 2012 Jan 26.
We examined the effects of acculturation, depressive symptoms, progesterone, and estriol (E3) as predictors of preterm birth (PTB) in pregnant Hispanic women. This cross-sectional study recruited a sample of 470 Hispanic women between 22- and 24-week gestation from physician practices and community clinics. We used the CES-D to measure maternal depressive symptoms. We measured acculturation by English proficiency on the Bidimensional Acculturation Scale, residence index by years in the USA minus age, nativity, and generational status. Serum progesterone and E3 were analyzed by EIA. Ultrasound and medical records determined gestational age after delivery. In χ (2) analysis, there were a significantly greater percentage of women with higher depressive scores if they were born in the USA. In a structural equation model (SEM), acculturation (English proficiency, residence index, and generational status) predicted the estriol/progesterone ratio (E/P), and the interaction of depressive symptoms with the E/P ratio predicted PTB. Undiagnosed depressive symptoms during pregnancy may have biological consequences increasing the risk for PTB.
我们研究了文化适应、抑郁症状、孕激素和雌三醇（E3）作为预测西班牙裔孕妇早产（PTB）的指标。这项横断面研究从医生诊所和社区诊所招募了 470 名 22-24 孕周的西班牙裔孕妇。我们使用 CES-D 来衡量产妇的抑郁症状。我们通过二维文化适应量表的英语熟练程度、在美国的居住年限减去年龄、出生地和代际状况来衡量文化适应程度。血清孕激素和 E3 采用 EIA 进行分析。超声和病历在分娩后确定了孕龄。在卡方分析中，如果女性出生在美国，那么具有较高抑郁评分的女性比例显著更高。在结构方程模型（SEM）中，文化适应（英语熟练程度、居住指数和代际状况）预测了雌三醇/孕激素比值（E/P），抑郁症状与 E/P 比值的相互作用预测了 PTB。怀孕期间未确诊的抑郁症状可能具有生物学后果，增加了 PTB 的风险。
