Bahrmann A, Bahrmann P, Kubiak T, Kopf D, Oster P, Sieber C C, Daniel W G
Medizinische Klinik 2, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Deutschland.
Z Gerontol Geriatr. 2012 Jan;45(1):17-22. doi: 10.1007/s00391-011-0269-z. Epub 2012 Jan 27.
Diabetes mellitus is a known risk factor for cognitive dysfunction and dementia. Chronic hyperglycemia, genetic predisposition, arterial hypertension, hyperlipoproteinemia, micro- and macrovascular diseases, and depression play a major role in the development of cognitive dysfunction. Both pathophysiology of diabetes and dementia and the specifics of diabetes therapy in patients with dementia are presented in this review.
糖尿病是认知功能障碍和痴呆症的已知危险因素。慢性高血糖、遗传易感性、动脉高血压、高脂蛋白血症、微血管和大血管疾病以及抑郁症在认知功能障碍的发展中起主要作用。本文综述了糖尿病和痴呆症的病理生理学以及痴呆症患者糖尿病治疗的具体情况。