酸橙汁和果皮提取物对低密度脂蛋白氧化的抗氧化作用。
Antioxidant effects of Citrus aurantifolia (Christm) juice and peel extract on LDL oxidation.
作者信息
Boshtam Maryam, Moshtaghian Jamal, Naderi Gholamali, Asgary Seddigheh, Nayeri Hashem
机构信息
Isfahan Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
出版信息
J Res Med Sci. 2011 Jul;16(7):951-5.
BACKGROUND
We studied the antioxidant effects of fresh juice and peel extract of Citrus aurantifolia (Christm).
METHODS
Low density lipoprotein (LDL) was separated from one hypercholesterolemic human serum by modified Bronzert and Brewer procedure. Oxidation of LDL was measured at 234 nm against 0, 5, 10, 20, 25, 30 and 40 μl of fresh lime juice and 0, 5, 10, 15 and 20 μl of peel polyphenolic extract solution in DMSO.
RESULTS
5 μl of lime juice didn't change LDL oxidation. 10 μl of juice inhibited LDL oxidation, and with increasing the juice concentration, LDL was oxidized faster. The higher concentrations of peel extract prevented LDL oxidation better than the lower ones.
CONCLUSIONS
Both juice and peel demonstrated antioxidant properties, but the excessive consumption of lime juice seems not to be beneficial. Regarding the intensity and type of flavonoids, lime juice and peel may show different effects.
背景
我们研究了酸橙（Citrus aurantifolia (Christm)）鲜榨果汁和果皮提取物的抗氧化作用。
方法
采用改良的Bronzert和Brewer方法从一名高胆固醇血症患者的血清中分离低密度脂蛋白（LDL）。在234 nm处测定LDL的氧化情况，分别加入0、5、10、20、25、30和40 μl鲜榨酸橙汁以及0、5、10、15和20 μl溶解于二甲基亚砜（DMSO）中的果皮多酚提取物溶液。
结果
5 μl酸橙汁未改变LDL的氧化情况。10 μl酸橙汁抑制了LDL的氧化，且随着果汁浓度增加，LDL氧化更快。较高浓度的果皮提取物比较低浓度的更能有效防止LDL氧化。
结论
果汁和果皮均具有抗氧化特性，但过量饮用酸橙汁似乎并无益处。就黄酮类化合物的强度和类型而言，酸橙汁和果皮可能表现出不同的作用。
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