巴西莲子草对皮肤烧伤创面愈合的影响。
Effect of Alternanthera brasiliana (L) Kuntze on healing of dermal burn wound.
作者信息
Baru Chandana C, Talukdar Archana, Begum Shameem A, Buragohain Bhaben, Roy Jayanti Datta, Pathak Debesh C, Sarma Dilip K, Gupta Asheesh K, Bora Rumi S
机构信息
Department of Veterinary Pharmacology and Toxicology, College of Veterinary Science, Assam Agricultural University, Khanapara, Guwahati 781 022, India.
出版信息
Indian J Exp Biol. 2012 Jan;50(1):56-60.
Wound healing activity of methanol extract of Alternanthera brasiliana [5% (w/w) ointment] was evaluated in experimental burn wound model in rats. Healing potential was assessed by the rate of wound contraction, estimation of anti-oxidants like catalase, superoxide dismutase, reduced glutathione, protein, vitamin C and hydroxyproline, along with histopathological examination on 8th day post wounding. The statistical data indicated that there was significant increase in wound contraction along with augmented level of antioxidants in granulation tissues in A. brasiliana treated group. Histopathological assessment of the granulation tissue revealed formation of epidermis with keratin layer and deposition of collagen fibers after treatment with the plant extract.
在大鼠实验性烧伤创面模型中评估了巴西莲子草甲醇提取物[5%（w/w）软膏]的伤口愈合活性。通过伤口收缩率、过氧化氢酶、超氧化物歧化酶、还原型谷胱甘肽、蛋白质、维生素C和羟脯氨酸等抗氧化剂的测定，以及伤后第8天的组织病理学检查来评估愈合潜力。统计数据表明，巴西莲子草治疗组的伤口收缩显著增加，同时肉芽组织中的抗氧化剂水平升高。对肉芽组织的组织病理学评估显示，用植物提取物处理后形成了具有角质层且有胶原纤维沉积的表皮。
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