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腱鞘巨细胞瘤:病例系列及文献综述

Giant cell tumor of tendon sheath: case series and review of literature.

作者信息

Suresh S S, Zaki Hosam

机构信息

Department of Orthopaedics, Ibri Regional Referral Hospital, PO Box 46, Ibri, 516 Sultanate of Oman.

出版信息

J Hand Microsurg. 2010 Dec;2(2):67-71. doi: 10.1007/s12593-010-0020-9. Epub 2010 Nov 18.

Abstract

Recurrence of Giant cell tumor of the tendon sheath (GCTTS) is an unresolved issue, though it is a non malignant condition. The authors operated on fourteen cases of GCTTS, after fine needle aspiration cytology confirmation and using a magnifying loupe for complete excision of the lesion including the satellite nodules. In only one case recurrence was noted which was successfully managed by a second wide excision. Preoperative diagnosis and meticulous surgical technique were found the only predictive factor of recurrence. During the 5 year period from 2002, 12 patients [11 females, 1 male, mean age 29.5, ranging from 10-53 years] underwent excision of giant cell tumor of tendon sheath of the hand. The lesions were found over the thumb [n = 7], ring finger [n = 1], index finger [n = 1], and over the hand [n = 2]. The lesions were classified using the Al-Qattan classification. The most common presentation was with a mass over the hand, with a predilection to the thumb [n = 7]. Radiological changes in the form of bony indentation was seen in only 2 cases. FNAC was inconclusive in 2 out of the 12 cases. Due to the high incidence of recurrence, pre-operative planning aided by a tissue diagnosis with fine needle aspiration cytology, wide surgical exposure, and meticulous dissection with help of magnification are imperative for a successful outcome in GCTTS.

摘要

腱鞘巨细胞瘤(GCTTS)的复发是一个尚未解决的问题,尽管它是一种非恶性疾病。作者对14例腱鞘巨细胞瘤患者进行了手术,术前经细针穿刺细胞学检查确诊,术中使用放大镜以完整切除病变,包括卫星结节。仅1例出现复发,经再次广泛切除成功处理。术前诊断和细致的手术技巧是发现复发的唯一预测因素。在2002年开始的5年期间,12例患者[11名女性,1名男性,平均年龄29.5岁,年龄范围为10 - 53岁]接受了手部腱鞘巨细胞瘤切除术。病变位于拇指[7例]、环指[1例]、食指[1例]及手部其他部位[2例]。采用Al-Qattan分类法对病变进行分类。最常见的表现是手部出现肿块,拇指受累最为常见[7例]。仅2例可见骨凹陷形式的放射学改变。12例中有2例细针穿刺抽吸活检结果不明确。由于复发率高,术前通过细针穿刺细胞学进行组织诊断、广泛的手术暴露以及在放大镜辅助下进行细致的解剖对于腱鞘巨细胞瘤手术成功至关重要。

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