Findling Robert L
Division of Child and Adolescent Psychiatry, University Hospitals of Cleveland, Case Western Reserve University, Cleveland, Ohio, USA.
J Clin Psychiatry. 2005;66 Suppl 10:26-31.
Autism and other pervasive developmental disorders (PDDs) are associated with various dysfunctional and problematic behaviors, in addition to the core features of language and social skills dysfunction that define these conditions. Although there is currently no pharmacologic cure for the core features of PDDs, some of the behavioral symptoms may be treated pharmacologically. In addition to relieving some of the daily stress in the lives of patients and their families, improvement of these behavioral symptoms, which include hyperactivity, aggression, tantrums, and self-injury, removes some of the hindrances to other rehabilitative efforts. This article discusses the efficacy and tolerability of various medications and alternative interventions in addressing the symptoms of autism and other PDDs.
自闭症和其他广泛性发育障碍（PDDs）除了具有定义这些病症的语言和社交技能功能障碍等核心特征外，还与各种功能失调和问题行为相关。虽然目前尚无针对PDDs核心特征的药物治疗方法，但某些行为症状可以通过药物治疗。除了缓解患者及其家人生活中的一些日常压力外，改善这些行为症状，包括多动、攻击行为、发脾气和自我伤害等，还能消除其他康复努力的一些障碍。本文讨论了各种药物和替代干预措施在治疗自闭症和其他PDDs症状方面的疗效和耐受性。
