Sun Yan-wu, Chi Pan, Lin Hui-ming, Lu Xing-rong, Huang Ying, Xu Zong-bin, Huang Sheng-hui
Department of Colon and Rectum Surgery, Fujian Medical University Union Hospital, Fuzhou, China.
Zhonghua Wei Chang Wai Ke Za Zhi. 2012 Jan;15(1):24-7.
To explore the differences in long-term outcomes between laparoscopic and open complete mesocolic excision(CME) for colon cancer.
A total of 273 patients with colon cancer who underwent CME at the Fujian Medical University Union Hospital from September 2000 to December 2008 were divided into laparoscopic(LP, n=147) and open(OP, n=126) groups in a non-random manner. The oncologic and long-term outcomes were compared.
No significant differences were seen in the length of distal and proximal margin, and number of lymph nodes(all P>0.05). Median postoperative follow up was 50 months. Local regional recurrence rates (LP 6.1% vs. OP 7.9%) and distal metastasis rates(LP 23.8% vs. OP 16.7%) were similar between the two groups(all P>0.05). The 5-year overall survival rates (LP 69.4% vs. OP 74.0%, P=0.840) and 5-year disease-free survival rates(LP 68.5% vs. OP 70.9%, P=0.668) between the two groups were not statistically different.
Laparoscopic CME has the same oncologic clearance effects compared with open CME for colon cancer. It might become a new standardized surgery for colon cancer.
探讨腹腔镜与开放完整结肠系膜切除术（CME）治疗结肠癌的远期疗效差异。
2000年9月至2008年12月在福建医科大学附属协和医院接受CME的273例结肠癌患者，非随机分为腹腔镜组（LP，n = 147）和开放组（OP，n = 126）。比较肿瘤学及远期疗效。
两组患者的远、近端切缘长度及淋巴结数目差异均无统计学意义（均P>0.05）。术后中位随访时间为50个月。两组局部区域复发率（LP 6.1% 对OP 7.9%）和远处转移率（LP 23.8% 对OP 16.7%）相似（均P>0.05）。两组5年总生存率（LP 69.4% 对OP 74.0%，P = 0.840）和5年无病生存率（LP 68.5% 对OP 70.9%，P = 0.668）差异无统计学意义。
腹腔镜CME治疗结肠癌与开放CME具有相同的肿瘤清除效果。它可能成为一种新的结肠癌标准化手术。
