Storli Kristian Eeg, Eide Geir Egil
Department of Surgery, Haraldsplass Deaconess Hospital, University of Bergen, Bergen, Norway.
Dig Surg. 2016;33(2):114-20. doi: 10.1159/000442716. Epub 2016 Jan 7.
BACKGROUND/AIM: Laparoscopic complete mesocolic excision (CME) used in the treatment of transverse colon cancer has been questioned on the basis of the technical challenges. The aim of this study was to evaluate the medium- and long-term clinical and survival outcomes after laparoscopic and open CME for transverse colon cancer and to compare the 2 approaches.
This study was a retrospective non-randomized study of patients with prospectively registered data on open and laparoscopic CME for transverse colon cancer tumour-node-metastasis stages I-III operated on between 2007 and 2014. This was a single-centre study in a community teaching hospital. A total of 56 patients with transverse colon cancer were included, excluding those with tumours in the colonic flexures. The outcome aims were 4-year time to recurrence (TTR) and cancer-specific survival (CSS). Morbidity was also measured.
The 4-year TTR was 93.9% in the laparoscopic group and 91.3% in the open group (p = 0.71). The 4-year CSS was 97.0% in the laparoscopic group and 91.3% in the open group (p = 0.42).
This was a prospective single-institution study with a small sample size.
Results of the study suggest that the laparoscopic CME approach might be the preferred approach for transverse colon cancer, especially regarding its benefits in terms of short-term morbidity, length of stay and oncological outcome.
背景/目的：腹腔镜全结肠系膜切除术（CME）用于治疗横结肠癌时，因其技术挑战而受到质疑。本研究的目的是评估腹腔镜和开放CME治疗横结肠癌后的中长期临床和生存结果，并比较这两种方法。
本研究是一项回顾性非随机研究，研究对象为2007年至2014年间接受开放和腹腔镜CME治疗的I-III期横结肠癌肿瘤-淋巴结-转移患者，其数据已前瞻性登记。这是一项在社区教学医院进行的单中心研究。共纳入56例横结肠癌患者，排除结肠弯曲处有肿瘤的患者。观察指标为4年复发时间（TTR）和癌症特异性生存（CSS）。还对发病率进行了测量。
腹腔镜组4年TTR为93.9%，开放组为91.3%（p = 0.71）。腹腔镜组4年CSS为97.0%，开放组为91.3%（p = 0.42）。
这是一项前瞻性单机构研究，样本量较小。
研究结果表明，腹腔镜CME方法可能是治疗横结肠癌的首选方法，特别是在短期发病率、住院时间和肿瘤学结果方面具有优势。
