Department of Otolaryngology-Head and Neck Surgery, University of Virginia Health System, Charlottesville, VA, USA.
Int Forum Allergy Rhinol. 2011 Jul-Aug;1(4):324-8. doi: 10.1002/alr.20054. Epub 2011 Apr 28.
Inverted papilloma is a benign sinonasal tumor that arises from a localized attachment site. These attachment sites, however, have not been fully characterized in the literature. The objective of this research was to determine the specific distribution of attachment sites in patients with sinonasal papilloma.
Retrospective analysis of adult patients with sinonasal papilloma presenting to the University of Virginia between 1999 and 2010. These patients were reviewed and compared to historical controls with regard to histologic subtype and pedicle attachment site.
A total of 83 patients were identified with 90 sites of attachment. For inverted/cylindrical papilloma, sites of attachment included the maxillary sinus (42%), ethmoid sinus (18%), nasal cavity (15%), middle/superior turbinate (12%), frontal sinus (10%), sphenoid sinus (1.5%), and cribriform plate (1.5%). Specific attachment sites within each group were identified, including 5 at the infraorbital nerve. The distribution of attachment sites differed significantly from historical controls resected via an open approach (p = 0.001), but did not differ significantly from historical controls endoscopically resected (p = 0.696). A comparison of more specific sites of attachments could not be performed due to the lack of this information in the literature.
The distribution of attachment sites in patients with sinonasal papilloma has changed as the endoscope has enabled more detailed identification of pedicle attachment, which has implications for management.
内翻性乳头状瘤是一种良性的鼻窦肿瘤,起源于局部附着部位。然而,这些附着部位在文献中尚未得到充分描述。本研究的目的是确定鼻窦乳头状瘤患者中附着部位的具体分布。
回顾性分析 1999 年至 2010 年间在弗吉尼亚大学就诊的成人鼻窦乳头状瘤患者。对这些患者进行了回顾性分析,并与历史对照组的组织学亚型和蒂部附着部位进行了比较。
共确定了 83 例患者,共有 90 个附着部位。对于内翻/圆柱状乳头状瘤,附着部位包括上颌窦(42%)、筛窦(18%)、鼻腔(15%)、中/上鼻甲(12%)、额窦(10%)、蝶窦(1.5%)和筛板(1.5%)。在每个组中都确定了特定的附着部位,包括 5 个位于眶下神经。与经开放入路切除的历史对照组相比,附着部位的分布差异有统计学意义(p = 0.001),但与经内镜切除的历史对照组相比差异无统计学意义(p = 0.696)。由于文献中缺乏这方面的信息,因此无法对更具体的附着部位进行比较。
随着内镜技术能够更详细地识别蒂部附着,鼻窦乳头状瘤患者的附着部位分布发生了变化,这对治疗有影响。