Partouche Henri, Benainous Olivier, Barthe Juliette, Pierret Janine, Rigal Laurent, Michaloux Maud, Gilberg Serge
Département de médecine générale, Université Paris Descartes, Sorbonne Paris Cité, faculté de médecine, Paris.
Rev Prat. 2011 Dec;61(10):1411-7.
The influenza A/H1N1 2009 immunization campaign did not have the accession of the French population resulting in a very low rate of immunization coverage. We conducted a cross-sectional study in spring 2010 to identify factors that led general practitionners (GPs) and their adult patients to be vaccinated or not; 43 GPs in France, included 668 patients; 29 GPs (67%) and 108 patients (16.5%) have been vaccinated; among 238 patients under vaccine priority indication 17% were vaccinated; 48% of patients thought they could receive effective treatment for influenza, 36% felt that the vaccine protected against influenza but 27% thought it did not meet usual safety criteria. A higher level of education, the belief of an effective protection with vaccination, the positive GP's opinion and behavior (OR 4,21 IC95% [1.4-14]; p=0.012), the receipt of an invitation to immunization (OR 7, 1 IC95% [1.73-58.4] and the active seek of information (OR 8.05, IC95% [2.8-27]) were significantly associated with vaccination. Regarding this immunization campaign few patients n=87 (13.7%) did trust the state heath agency. Our study confirms the distrust of the vaccine and suggests the decisive role of the GPs to achieve adequate levels of immunization coverage.
2009年甲型H1N1流感免疫接种活动并未得到法国民众的支持，导致免疫接种覆盖率极低。我们在2010年春季进行了一项横断面研究，以确定导致全科医生（GPs）及其成年患者接种或未接种疫苗的因素；法国的43名全科医生纳入了668名患者；29名全科医生（67%）和108名患者（16.5%）接种了疫苗；在238名有疫苗优先接种指征的患者中，17%接种了疫苗；48%的患者认为他们可以接受有效的流感治疗，36%的患者认为疫苗可预防流感，但27%的患者认为它不符合通常的安全标准。较高的教育水平、相信接种疫苗能有效预防、全科医生的积极意见和行为（比值比4.21，95%置信区间[1.4 - 14]；p = 0.012）、收到免疫接种邀请（比值比7.1，95%置信区间[1.73 - 58.4]）以及积极寻求信息（比值比8.05，95%置信区间[2.8 - 27]）与接种疫苗显著相关。关于这次免疫接种活动，很少有患者（n = 87，13.7%）信任国家卫生机构。我们的研究证实了对疫苗的不信任，并表明全科医生在实现足够的免疫接种覆盖率方面具有决定性作用。
