Division of Adult and Community Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, 4770 Buford Hwy, MS K67, Atlanta, GA 30341, USA.
Circulation. 2012 Feb 28;125(8):987-95. doi: 10.1161/CIRCULATIONAHA.111.049122. Epub 2012 Jan 30.
Recently, the American Heart Association developed a set of 7 ideal health metrics that will be used to measure progress toward their 2020 goals for cardiovascular health. The objective of the present study was to examine how well these metrics predicted mortality from all causes and diseases of the circulatory system in a national sample of adults in the United States.
We used data from 7622 adults ≥20 years of age who participated in the National Health and Nutrition Examination Survey from 1999 to 2002 and whose mortality through 2006 was determined via linkage to the National Death Index. For the dietary and glycemic metrics, we used alternative measures. During a median follow-up of 5.8 years, 532 deaths (186 deaths resulting from diseases of the circulatory system) occurred. About 1.5% of participants met none of the 7 ideal cardiovascular health metrics, and 1.1% of participants met all 7 metrics. The number of ideal metrics was significantly and inversely related to mortality from all causes and diseases of the circulatory system. Compared with participants who met none of the ideal metrics, those meeting ≥5 metrics had a reduction of 78% (adjusted hazard ratio, 0.22; 95% confidence interval, 0.10-0.50) in the risk for all-cause mortality and 88% (adjusted hazard ratio, 0.12; 95% confidence interval, 0.03-0.57) in the risk for mortality from diseases of the circulatory system.
The number of ideal cardiovascular health metrics is a strong predictor of mortality from all causes and diseases of the circulatory system.
最近，美国心脏协会制定了一套 7 项理想健康指标，用于衡量其 2020 年心血管健康目标的进展情况。本研究的目的是检验这些指标在美国成年人全国样本中对所有原因和循环系统疾病死亡率的预测能力。
我们使用了来自 1999 年至 2002 年参加国家健康和营养调查的 7622 名年龄≥20 岁的成年人的数据，这些成年人的死亡率通过与国家死亡指数的链接来确定。对于饮食和血糖指标，我们使用了替代指标。在中位数为 5.8 年的随访期间，发生了 532 例死亡（186 例死于循环系统疾病）。大约有 1.5%的参与者一项理想心血管健康指标都不符合，而 1.1%的参与者符合所有 7 项指标。符合理想指标的数量与所有原因和循环系统疾病的死亡率呈显著负相关。与不符合任何理想指标的参与者相比，符合≥5 项理想指标的参与者全因死亡率降低了 78%（调整后的危险比，0.22；95%置信区间，0.10-0.50），死于循环系统疾病的风险降低了 88%（调整后的危险比，0.12；95%置信区间，0.03-0.57）。
理想心血管健康指标的数量是所有原因和循环系统疾病死亡率的强有力预测指标。
