Warashina Tsutomu, Umehara Kaoru, Miyase Toshio
Institute for Environmental Sciences, University of Shizuoka, 52–1 Yada, Suruga-ku, Shizuoka, Japan.
Chem Pharm Bull (Tokyo). 2012;60(2):205-12. doi: 10.1248/cpb.60.205.
A MeOH extract from the roots of Taraxacum platycarpum has shown significant effects on the proliferation of normal human skin fibroblasts. Chemical analysis of the extract resulted in the isolation of 26 compounds, including eight new triterpenes, one new sesquiterpene glycoside, and seventeen known compounds. The structure of each new compound was established using NMR spectroscopy. Some triterpenes had a significant effect on the proliferation of normal human skin fibroblasts.
阔叶蒲公英根的甲醇提取物对正常人皮肤成纤维细胞的增殖显示出显著作用。对该提取物进行化学分析后分离出26种化合物，包括8种新的三萜类化合物、1种新的倍半萜糖苷和17种已知化合物。每种新化合物的结构通过核磁共振光谱确定。一些三萜类化合物对正常人皮肤成纤维细胞的增殖有显著影响。
