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新诊断的 2 型糖尿病患者的管理:医生的态度如何?SUBITO!AMD 对意大利早期糖尿病治疗的调查。

Management of newly diagnosed patients with type 2 diabetes: what are the attitudes of physicians? A SUBITO!AMD survey on the early diabetes treatment in Italy.

机构信息

Diabetes Unit, Sandro Pertini Hospital, Rome, Italy.

出版信息

Acta Diabetol. 2012 Dec;49(6):429-33. doi: 10.1007/s00592-012-0374-5.

Abstract

Early intensive therapy in type 2 diabetes can prevent complications. Nevertheless, metabolic control is often sub-optimal in newly diagnosed patients. This web-based survey aimed to evaluate opinions of physicians about treatment, priorities, and barriers in the care of patients first referred to diabetes clinics. Data on physician attitudes toward therapeutic preferences for two clinical case models (same clinical profile, except HbA1c levels of 8.6 and 7.3% at the first access, respectively) were collected. Participants were asked to rank from 1 (most important) to 6 (least important) a list of priorities and barriers associated with the care of new patients. Overall, 593 physicians participated. In both case models, metformin and education were primary options, although their combination with other classes of drugs varied substantially. Main priorities were "to teach the patient how to cope with the disease" and "to achieve HbA1c target"; main barriers were "lack of time" and "long waiting list". At multivariate analyses, physicians from the South of Italy had a twofold higher likelihood to attribute a rank 1–2 to organizational barriers than those operating in the North (South vs. North: OR: 2.4; 95% CI 1.4–4.1; Center vs. North: OR: 2.4; 95% CI 0.9–3.2). In the absence of a widely accepted evidence-based therapeutic algorithm driving the therapeutic choices according to the patient characteristics, prescriptions vary according to physician preferences. Education is perceived as a key-strategy, but organizational barriers and geographic disparities are an obstacle. These findings can drive new strategies to reduce clinical inertia, attitudes variability, and geographic disparities.

摘要

早期强化治疗 2 型糖尿病可以预防并发症。然而,新诊断的患者代谢控制往往不理想。这项基于网络的调查旨在评估医生对首次就诊于糖尿病诊所患者的治疗、优先事项和治疗障碍的看法。收集了关于医生对两种临床病例模型(临床特征相同,仅在首次就诊时的 HbA1c 水平分别为 8.6%和 7.3%)治疗偏好的态度数据。参与者被要求对与新患者护理相关的优先事项和障碍列表进行排名,从 1(最重要)到 6(最不重要)。共有 593 名医生参与了这项调查。在两种病例模型中,二甲双胍和教育都是主要选择,尽管它们与其他类别的药物联合使用存在很大差异。主要的优先事项是“教导患者如何应对疾病”和“实现 HbA1c 目标”;主要障碍是“缺乏时间”和“长候诊名单”。在多变量分析中,来自意大利南部的医生比北部的医生更有可能将组织障碍列为 1-2 级(南部与北部相比:OR:2.4;95%CI 1.4-4.1;中心与北部相比:OR:2.4;95%CI 0.9-3.2)。在缺乏广泛接受的循证治疗算法根据患者特征指导治疗选择的情况下,处方会因医生的偏好而有所不同。教育被认为是一项关键策略,但组织障碍和地域差异是一个障碍。这些发现可以推动新的策略来减少临床惰性、态度差异和地域差异。

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