来自南蛇藤的两种新木脂素

Two new lignans from Celastrus flagellaris Rupr.

作者信息

Zhao Xue-Mei, Guo Fu-Jiang, Li Yi-Ming, Zhu Da-Yuan

机构信息

Pharmacy College, Taishan Medical University, Tai'an, China.

出版信息

J Asian Nat Prod Res. 2012;14(2):159-64. doi: 10.1080/10286020.2011.641535.

DOI:10.1080/10286020.2011.641535

PMID:22296156

Abstract

Two new lignans (R-biar)-12-angeloyloxy-6,7,8,9-tetrahydro-1,2,3,13,14-pentamethoxy-7,8-dimethyl-7-dibenzo[a,c]cyclooctenol (1) and (R-biar)-12-benzoyloxy-6,7,8,9-tetrahydro-1,2,3,13,14-pentamethoxy-7,8-dimethyl-7-dibenzo[a,c]cyclooctenol (2) were isolated from the stems of Celastrus flagellaris Rupr. Their structures were elucidated on the basis of spectroscopic methods including HR-EI-MS, 1D and 2D NMR, HMQC, NOESY, and CD.

摘要

从大花卫矛（Celastrus flagellaris Rupr.）的茎中分离出两种新的木脂素：(R-biar)-12-当归酰氧基-6,7,8,9-四氢-1,2,3,13,14-五甲氧基-7,8-二甲基-7-二苯并[a,c]环辛烯醇（1）和(R-biar)-12-苯甲酰氧基-6,7,8,9-四氢-1,2,3,13,14-五甲氧基-7,8-二甲基-7-二苯并[a,c]环辛烯醇（2）。通过包括高分辨电子轰击质谱（HR-EI-MS）、一维和二维核磁共振（1D和2D NMR）、异核多量子相干（HMQC）、核欧沃豪斯效应光谱（NOESY）和圆二色光谱（CD）在内的光谱方法对其结构进行了阐明。