University of Toronto, ON, Canada.
Int Wound J. 2012 Dec;9(6):683-92. doi: 10.1111/j.1742-481X.2012.00939.x. Epub 2012 Feb 2.
A prospective case series was studied to assess the potential for complete healing of wounds among patients with advanced illness referred to a regional palliative care program in Toronto, Canada. Two hundred and eighty-two patients, of which 148 were primarily diagnosed with cancer and 134 with non cancer advanced illness, were assessed and followed until their deaths. On the baseline initial referral date, 823 wounds were documented. The wound classes assessed included pressure ulcers, malignant wounds, skin tears, venous leg ulcers, diabetic foot ulcers and arterial leg/foot ulcers. Proportions of patients showing complete healing of at least one wound were calculated, stratified by patient's survival time post-baseline (1 week, 1 month, 3 months and 6 months). Proportions of patients showing complete healing of at least one wound increased the longer patients lived and ranged between 12·9% and 43·5% for stage I pressure ulcers, 0% and 60% for stage II pressure ulcers, 2·4% and 100% for skin tears, 10% and 100% for venous leg ulcers and 0% and 50% for diabetic foot ulcers. Only one person showed complete healing of a stage III pressure ulcer and no complete healing was observed with stage IV pressure ulcers, unstageable pressure ulcers, malignant wounds and arterial leg/foot ulcers.
一项前瞻性病例系列研究评估了加拿大多伦多地区姑息治疗项目中晚期疾病患者的伤口完全愈合的可能性。对 282 名患者进行了评估和随访，直到他们死亡，其中 148 名患者主要被诊断为癌症，134 名患者患有非癌症晚期疾病。在基线初始转介日期，记录了 823 处伤口。评估的伤口类别包括压疮、恶性伤口、皮肤撕裂、静脉腿部溃疡、糖尿病足溃疡和动脉腿部/脚部溃疡。根据患者在基线后（1 周、1 个月、3 个月和 6 个月）的存活时间，计算出至少有一处伤口完全愈合的患者比例。存活时间越长，至少有一处伤口完全愈合的患者比例越高，I 期压疮为 12.9%至 43.5%，II 期压疮为 0%至 60%，皮肤撕裂为 2.4%至 100%，静脉腿部溃疡为 10%至 100%，糖尿病足溃疡为 0%至 50%。只有 1 人完全愈合了 III 期压疮，没有观察到 IV 期压疮、无法分期的压疮、恶性伤口和动脉腿部/脚部溃疡完全愈合。
