Lahera Guillermo, Ruiz-Murugarren Salvador, Iglesias Paloma, Ruiz-Bennasar Claudia, Herrería Elvira, Montes José Manuel, Fernández-Liria Alberto
Principe de Asturias University Hospital, University of Alcala, Madrid, Spain.
J Nerv Ment Dis. 2012 Feb;200(2):135-41. doi: 10.1097/NMD.0b013e3182438eae.
The purpose of this study was to assess the role of social cognition, together with other relevant clinical variables and measures of general cognition, in the global functioning of euthymic bipolar patients. Thirty-nine euthymic outpatients fulfilling DSM-IV-TR criteria for bipolar disorder type I or II were recruited and were divided in two groups: high (n = 19) and low (n = 20) global functioning. Both groups' performance was compared in verbal and nonverbal social cognition (Faux pas test and Facial Emotion Recognition test), sustained attention and executive function. The low-functioning group showed a significant impairment in both verbal and nonverbal measurements of social cognition compared with the high-functioning group. Globally, both bipolar groups showed a significant impairment in facial emotion recognition compared with a similar sample of healthy volunteers. Social cognition may play a significant role in the clinical-functional gap of bipolar patients.
本研究的目的是评估社会认知，以及其他相关临床变量和一般认知测量指标，在双相情感障碍缓解期患者整体功能中的作用。招募了39名符合DSM-IV-TR中I型或II型双相情感障碍标准的缓解期门诊患者，并将其分为两组：整体功能高的组（n = 19）和整体功能低的组（n = 20）。比较了两组在言语和非言语社会认知（失言测试和面部表情识别测试）、持续注意力和执行功能方面的表现。与高功能组相比，低功能组在社会认知的言语和非言语测量方面均表现出显著受损。总体而言，与健康志愿者的类似样本相比，两个双相情感障碍组在面部表情识别方面均表现出显著受损。社会认知可能在双相情感障碍患者的临床功能差距中发挥重要作用。
