Taneja Sonali, Kumari Manju
Department of Conservative Dentistry and Endodontics, ITS-Centre for Dental Studies and Research, Muradnagar, Uttar Pradesh, India.
J Investig Clin Dent. 2012 Feb;3(1):72-6. doi: 10.1111/j.2041-1626.2011.00082.x. Epub 2011 Aug 11.
Microorganisms are the possible source of endodontic lesions. The polymicrobial infection makes the sterilization of the root canal difficult. The following case report describes the non-surgical endodontic treatment of teeth with a large periradicular lesion. First, an intracanal dressing of calcium hydroxide was given. Since the symptoms did not subside, the treatment protocol was changed. A triple antibiotic paste was used instead for 3 months. On follow up, teeth were clinically asymptomatic and radiographically showed healing of the periradicular lesion. The result of the case show that when most commonly-used medicaments fail in eliminating the symptoms, then a triple antibiotic paste (metronidazole, ciprofloxacin, and minocycline) can be used clinically in the treatment of teeth with large periradicular lesions.
微生物是牙髓病变的可能来源。混合微生物感染使得根管消毒变得困难。以下病例报告描述了对患有较大根尖周病变牙齿的非手术根管治疗。首先，进行了氢氧化钙根管内封药。由于症状未消退，治疗方案发生了改变。取而代之的是使用三联抗生素糊剂，持续3个月。在随访中，牙齿临床无症状，影像学显示根尖周病变愈合。该病例结果表明，当最常用的药物无法消除症状时，三联抗生素糊剂（甲硝唑、环丙沙星和米诺环素）可在临床上用于治疗患有较大根尖周病变的牙齿。
