Kumar N Kiran, Brigit Biji, Annapoorna B S, Naik Savitha B, Merwade Seema, Rashmi K
Department of Conservative Dentistry and Endodontics, Government Dental College, Bengaluru, Karnataka, India.
J Conserv Dent. 2021 Jul-Aug;24(4):307-313. doi: 10.4103/jcd.jcd_637_20. Epub 2022 Jan 13.
The rate of healing of periapical lesion after the antibacterial dressing with triple antibiotic paste and calcium hydroxide was assessed.
Case reports which used triple antibiotic paste and calcium hydroxide as the intracanal dressing was searched in PubMed, Google Scholar and Cochrane Oral Health's Trials Register up to August 2020, without language and period restriction. Two authors independently reviewed all identified titles and abstracts for eligibility. Tables were generated to summarize the included studies.
Sixteen ( = 16) articles met the eligibility criteria. Nonsurgical endodontic treatment was carried out in eleven cases with triple antibiotic paste and in nineteen cases calcium hydroxide was used. Results of the study after analyzing the case reports indicate that both triple antibiotic paste and calcium hydroxide are equally effective as intracanal medicament. In cases where calcium hydroxide failed to eliminate symptoms, triple antibiotic paste was found to be effective.
As far as the effect on the healing of the periapical lesions is concerned, all the studies showed a high success rate. Available scientific data indicates nonsurgical treatment can be adopted as a routine measure to conservatively treat large periapical lesions of endodontic origin.
评估使用三联抗生素糊剂和氢氧化钙进行抗菌敷料后根尖周病变的愈合率。
截至2020年8月，在PubMed、谷歌学术和考克兰口腔健康试验注册库中检索以三联抗生素糊剂和氢氧化钙作为根管内敷料的病例报告，无语言和时间限制。两位作者独立审查所有识别出的标题和摘要以确定是否符合纳入标准。生成表格以总结纳入的研究。
16篇文章符合纳入标准。11例使用三联抗生素糊剂进行非手术根管治疗，19例使用氢氧化钙。分析病例报告后的研究结果表明，三联抗生素糊剂和氢氧化钙作为根管内药物同样有效。在氢氧化钙未能消除症状的病例中，发现三联抗生素糊剂有效。
就对根尖周病变愈合的影响而言，所有研究均显示出较高的成功率。现有科学数据表明，非手术治疗可作为保守治疗牙髓源性大型根尖周病变的常规措施。
