King Saud University, Riyadh, Saudi Arabia.
Int J Oral Maxillofac Implants. 2012 Jan-Feb;27(1):77-83.
The present study aimed to evaluate and compare two types of implants: grit-blasted and acidetched implants (SLActive) and nanometer-scale hydroxyapatite-modified implants (NanoTite).
Twenty-two SLActive and 22 NanoTite implants were inserted into the mandibles of 11 beagle dogs. The animals were divided into three groups according to healing time (group A, 2 weeks; group B, 4 weeks; group C, 8 weeks). Resonance frequency analysis (RFA) was performed immediately after implant placement and after 2, 4, and 8 weeks of healing. Two, 4, and 8 weeks after implantation, the animals were sacrificed and the amount of bone surrounding the implants was assessed using microcomputed tomography.
For SLActive and NanoTite implants, the RFA values decreased after 2 weeks and increased after 4 and 8 weeks of healing. After 8 weeks, the mean RFA value for SLActive implants was significantly higher than the mean RFA value for NanoTite implants. For the different healing periods, no significant differences in bone volume were seen for SLActive and NanoTite implants.
SLActive and NanoTite implants evoked a similar bone response after implantation for 2, 4, and 8 weeks in a nonsubmerged position in the mandibles of dogs. In addition, the data confirmed that RFA is a reliable and noninvasive method to determine dental implant stability and the bone formation process at the clinical level.
本研究旨在评估和比较两种类型的种植体：喷砂酸蚀种植体（SLActive）和纳米羟基磷灰石改性种植体（NanoTite）。
将 22 个 SLActive 和 22 个 NanoTite 种植体植入 11 只比格犬的下颌骨中。根据愈合时间将动物分为三组（A 组，2 周；B 组，4 周；C 组，8 周）。种植体放置后立即进行共振频率分析（RFA），并在愈合后 2、4 和 8 周进行检测。种植后 2、4 和 8 周，处死动物，使用微计算机断层扫描评估种植体周围的骨量。
对于 SLActive 和 NanoTite 种植体，RFA 值在 2 周后降低，在 4 和 8 周愈合后增加。8 周后，SLActive 种植体的平均 RFA 值明显高于 NanoTite 种植体的平均 RFA 值。对于不同的愈合期，SLActive 和 NanoTite 种植体的骨体积无显著差异。
在非淹没状态下，SLActive 和 NanoTite 种植体在植入犬下颌骨 2、4 和 8 周后引起相似的骨反应。此外，数据证实 RFA 是一种可靠的、非侵入性的方法，可在临床水平上确定牙种植体稳定性和骨形成过程。
