Liew N C, Moissinac K, Lee Limi, Gee Tikfu, Zezeman R B H Raja
Department of Surgery, University Putra Malaysia, Penang Medical College, Penang.
Med J Malaysia. 2011 Oct;66(4):386-8; quiz 389.
There has been much progress made in the management of peripheral arterial disease (PAD) in the past two decades. Progress in the understanding of the endothelial-platelet interaction during health and disease state have resulted in better antiplatelet drugs that can prevent platelet aggregation, activation and thrombosis during angioplasty and stenting. Collaborative effort by different international societies has resulted in a consensus guideline that recommends the modality of intervention in certain disease states. Progress in perioperative care has reduced the morbidity and mortality associated with peripheral vascular reconstruction surgery. Nevertheless, the advances in percutaneous peripheral intervention (PPI) have made a paradigm shift in the current management of patients. The procedure is safe and effective and is emerging as the first choice revascularization procedure.
在过去二十年中，外周动脉疾病（PAD）的管理取得了很大进展。对健康和疾病状态下内皮-血小板相互作用的理解取得的进展，带来了更好的抗血小板药物，这些药物可以在血管成形术和支架置入过程中预防血小板聚集、激活和血栓形成。不同国际协会的共同努力产生了一项共识指南，该指南推荐了某些疾病状态下的干预方式。围手术期护理的进展降低了与外周血管重建手术相关的发病率和死亡率。尽管如此，经皮外周介入治疗（PPI）的进展使当前患者管理发生了范式转变。该手术安全有效，正成为血管重建的首选手术。
