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胃手术后的淤滞综合征:60例有症状患者的临床和动力特征

Stasis syndromes following gastric surgery: clinical and motility features of 60 symptomatic patients.

作者信息

Fich A, Neri M, Camilleri M, Kelly K A, Phillips S F

机构信息

Gastroenterology Research Unit, Mayo Clinic and Foundation, Rochester, Minnesota 55905.

出版信息

J Clin Gastroenterol. 1990 Oct;12(5):505-12.

PMID:2229993
Abstract

We retrospectively reviewed the records of 60 patients who had been referred for gastrointestinal manometry because of stasis after gastric surgery. Nausea, vomiting, bloating, abdominal pain, and weight loss were the most common symptoms. Two thirds of these patients had a well-documented history of peptic ulcer before their initial operations; in others, surgery was performed for other reasons, such as obesity (5%) or reflux esophagitis (8%). Twelve patients had undergone truncal vagotomy and a "drainage operation" and 48 had received a partial gastrectomy with a gastroenterostomy: Billroth I (n = 8), Billroth II (n = 11), Roux-en-Y (n = 29). All patients had recordings of gastrointestinal manometry; 16 also had a scintigraphic measurement of gastric emptying. Measurements were compared with data from healthy controls. Gastric manometry, which could be assessed only in the group with an intact antrum, was characterized by antral hypomotility (p less than 0.05). Gastric emptying studies showed rapid early emptying of liquids and delayed emptying of solids (both p less than 0.05). In the whole group, fasting jejunal motility was characterized by absence of phase II in 13, presence of bursts of phasic activity in 18, and abnormal propagation of phase III in 8. A significantly increased frequency of phase III of MMC was noted in the patients after Billroth II and Roux-en-Y operations. Postprandially, 19 patients failed to develop a "fed pattern."(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

我们回顾性分析了60例因胃手术后出现淤滞而接受胃肠测压检查的患者记录。恶心、呕吐、腹胀、腹痛和体重减轻是最常见的症状。这些患者中有三分之二在初次手术前有明确记录的消化性溃疡病史;其他患者则因其他原因接受手术,如肥胖(5%)或反流性食管炎(8%)。12例患者接受了迷走神经切断术和“引流手术”,48例接受了胃部分切除术并进行了胃肠吻合术:毕罗一世式(n = 8)、毕罗二世式(n = 11)、Roux-en-Y式(n = 29)。所有患者均进行了胃肠测压记录;16例还进行了胃排空的闪烁扫描测量。将测量结果与健康对照数据进行比较。仅在胃窦完整的组中可评估胃测压,其特征为胃窦运动减弱(p < 0.05)。胃排空研究显示液体早期排空迅速,固体排空延迟(均p < 0.05)。在整个组中,空腹空肠运动的特征为:13例无II期,18例有阶段性活动爆发,8例III期传播异常。毕罗二世式和Roux-en-Y式手术后患者的MMC III期频率显著增加。餐后,19例患者未能形成“进食模式”。(摘要截短至250字)

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