Galgiani J N, Ampel N M
Medical Service, VA Medical Center, Tucson, AZ 85723.
J Infect Dis. 1990 Nov;162(5):1165-9. doi: 10.1093/infdis/162.5.1165.
Coccidioidomycosis is at best a complicated fungal infection; often it is life-threatening. Coccidioidomycosis is confined epidemiologically to the southwestern region of the USA, and most cases have occurred in that area, particularly in Arizona. However, we have seen several cases in San Francisco in patients with only a history of travel to endemic areas. In part because of its regional distribution, information about the clinical presentation, diagnosis, and treatment of patients with coccidioidomycosis has lagged behind information about other, more commonly encountered AIDS-associated opportunistic infections. Drs. Galgiani and Ampel have probably had the largest single experience with coccidioidomycosis in individuals infected with the human immunodeficiency virus. These specialists share their experience and make recommendations as to how these complicated conditions should be approached.
球孢子菌病往好了说是一种复杂的真菌感染；通常它会危及生命。从流行病学角度来看，球孢子菌病局限于美国西南部地区，大多数病例都发生在该地区，尤其是亚利桑那州。然而，我们在旧金山也见过几例患者，他们仅有前往该病流行地区的旅行史。部分由于其地区分布特点，关于球孢子菌病患者临床表现、诊断和治疗的信息，滞后于关于其他更常见的艾滋病相关机会性感染的信息。加尔贾尼医生和安佩尔医生在感染人类免疫缺陷病毒的个体中治疗球孢子菌病方面，可能有着最为丰富的单一经验。这些专家分享了他们的经验，并就如何应对这些复杂病情提出了建议。
