MMWR Morb Mortal Wkly Rep. 1996 Dec 13;45(49):1069-73.
Coccidioidomycosis is a systemic infection caused by the inhalation of airborne arthroconidia from Coccidioides immitis, a soil-dwelling fungus found in the southwestern United States, parts of Mexico, and Central and South America. Clinical manifestations occur in approximately 40% of infected persons and may include mild influenza-like illness; severe pneumonia; and rarely, disseminated disease and death. During 1990-1995, the number of reported cases of coccidioidomycosis in Arizona increased by 144%. To characterize trends in and the impact of coccidioidomycosis in Arizona, the Arizona Department of Health Services (ADHS) analyzed surveillance, death-certificate, and hospital discharge data. This report summarizes the findings, which indicate that, during 1990-1995, coccidioidomycosis in Arizona disproportionately affected persons aged > or = 65 years and persons with human immunodeficiency virus (HIV) infection.
球孢子菌病是一种由吸入土壤真菌粗球孢子菌的气传关节孢子引起的全身性感染。粗球孢子菌是一种土壤真菌，在美国西南部、墨西哥部分地区以及中美洲和南美洲均有发现。约40%的感染者会出现临床表现，可能包括轻度流感样疾病、严重肺炎，极少数情况下会出现播散性疾病和死亡。1990 - 1995年期间，亚利桑那州报告的球孢子菌病病例数增加了144%。为了描述亚利桑那州球孢子菌病的发病趋势及其影响，亚利桑那州卫生服务部（ADHS）分析了监测数据、死亡证明数据和医院出院数据。本报告总结了研究结果，结果表明，在1990 - 1995年期间，亚利桑那州的球孢子菌病对65岁及以上人群和感染人类免疫缺陷病毒（HIV）的人群影响尤为严重。
